Poplausky M R, Kaufman J A, Geller S C, Waltman A C
Department of Vascular and Interventional Radiology, Massachusetts General Hospital, Boston, USA.
Gastroenterology. 1996 May;110(5):1633-5. doi: 10.1053/gast.1996.v110.pm8613072.
A 77-year-old man with a history of multiple surgically treated malignancies presented with increasing abdominal pain after eating. Computerized tomographic scan showed superior mesenteric vein and portal vein thrombosis. The patient was treated with selective superior mesenteric artery infusion of urokinase resulting in clinical improvement and near complete resolution of the mesenteric venous thrombosis. An underlying gastric malignancy was found and is believed to be the cause of the patient's hypercoagulable state. Direct infusion of urokinase into the superior mesenteric artery for treatment of mesenteric venous thrombosis is an alternative to surgery in selected patients and an alternative to the much more complicated delivery systems presently used.
一名77岁男性，有多次手术治疗恶性肿瘤病史，进食后出现腹痛加重。计算机断层扫描显示肠系膜上静脉和门静脉血栓形成。该患者接受了选择性肠系膜上动脉尿激酶灌注治疗，临床症状改善，肠系膜静脉血栓几乎完全消退。发现潜在的胃恶性肿瘤，认为这是患者高凝状态的原因。对于选定患者，将尿激酶直接注入肠系膜上动脉治疗肠系膜静脉血栓是手术的一种替代方法，也是目前使用的更为复杂的给药系统的一种替代方法。
