Whittaker J A, Griffith I P
Br Med J. 1977 May 14;1(6071):1251-2. doi: 10.1136/bmj.1.6071.1251.
Three patients receiving vincristine or binblastine developed recurrent laryngeal nerve paralysis, which resolved when the drug was withdrawn. The presence of mediastinal lymphadenopathy in patients with lymphoma may obscure the correct diagnosis, with the danger that the condition will produce respiratory distress if vinca alkaloid treatment is continued.
三名接受长春新碱或长春碱治疗的患者出现了喉返神经麻痹,停药后症状缓解。淋巴瘤患者纵隔淋巴结肿大可能会掩盖正确诊断,存在如果继续使用长春花生物碱治疗病情将导致呼吸窘迫的风险。