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Bilateral recurrent laryngeal nerve palsy resulting from treatment with vincristine.长春新碱治疗导致双侧喉返神经麻痹。
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Vincristine-induced laryngeal nerve paralysis.长春新碱引起的喉返神经麻痹。
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本文引用的文献

1
THE VINCA ALKALOIDS: A NEW CLASS OF ONCOLYTIC AGENTS.长春花生物碱：一类新型溶瘤剂。
Cancer Res. 1963 Sep;23:1390-427.
2
Vincristine in the treatment of lymphomas and leukemias.长春新碱在淋巴瘤和白血病治疗中的应用。
Cancer Res. 1963 May;23:613-21.
3
Vocal cord paralysis: a toxic reaction to vinblastine (NSC-49842) therapy.声带麻痹：长春碱（NSC - 49842）治疗的毒性反应。
Cancer Chemother Rep. 1971 Dec;55(5):591-3.
4
Vincristine treatment of advanced cancer: a cooperative study of 392 cases.长春新碱治疗晚期癌症：392例合作研究。
Cancer Res. 1973 Jun;33(6):1258-64.
5
Vincristine neuropathy. Clinical and electrophysiological observations.长春新碱神经病变。临床及电生理观察
Brain. 1973;96(1):69-86. doi: 10.1093/brain/96.1.69.

接受长春新碱和长春碱治疗的患者出现喉返神经麻痹。

Recurrent laryngeal nerve paralysis in patients receiving vincristine and vinblastine.

作者信息

Whittaker J A, Griffith I P

出版信息

Br Med J. 1977 May 14;1(6071):1251-2. doi: 10.1136/bmj.1.6071.1251.

DOI:10.1136/bmj.1.6071.1251
PMID:861561
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1607088/
Abstract

Three patients receiving vincristine or binblastine developed recurrent laryngeal nerve paralysis, which resolved when the drug was withdrawn. The presence of mediastinal lymphadenopathy in patients with lymphoma may obscure the correct diagnosis, with the danger that the condition will produce respiratory distress if vinca alkaloid treatment is continued.

摘要

三名接受长春新碱或长春碱治疗的患者出现了喉返神经麻痹，停药后症状缓解。淋巴瘤患者纵隔淋巴结肿大可能会掩盖正确诊断，存在如果继续使用长春花生物碱治疗病情将导致呼吸窘迫的风险。