Dritz S S, Chengappa M M, Nelssen J L, Tokach M D, Goodband R D, Nietfeld J C, Staats J J
Department of Animal Sciences and Industry, Kansas State University, Manhattan 66506-0201, USA.
J Am Vet Med Assoc. 1996 Mar 1;208(5):711-5.
To determine whether segregated, early weaned pigs have better growth performance and different microbial flora than those pigs raised on-site.
Prospective, observational study.
Pigs from a commercial operation that were known to be infected with several common swine pathogens.
Pigs (7 to 10 days old) were weaned and segregated from the farm of origin and compared with littermate control pigs (14 to 17 days old) that were weaned and raised on-site. Pig weight was measured and microbial flora were isolated at 14-day intervals for 84 days, beginning when the pigs were 7 to 10 days old.
At 50 days of age, the segregated, early weaned pigs had a mean weight of 23.7 kg, compared with a mean weight of 12.5 kg for control pigs. Pasteurella multocida was isolated from fewer segregated, early weaned pigs than from controls. Signs of Mycoplasma hyopneumoniae infection were detected in control pigs but not in segregated early weaned pigs. Clinical, serologic, or bacteriologic signs of early postnatal vertical transmission of Actinobacillus pleuropneumoniae were not detected in either group.
Vertical transmission of M hyopneumoniae was prevented by weaning pigs at 7 to 10 days of age and segregating them off-site, without the use of medication. Although medicated controls were not compared, results from this herd revealed that use of antibiotics is not the most important factor for disease control in segregated, early weaning programs. Minimizing antibiotic use in disease-control protocols reduces costs as well as removes the need for extra-label drugs.
确定与场内饲养的猪相比，隔离饲养的早期断奶仔猪是否具有更好的生长性能以及不同的微生物菌群。
前瞻性观察性研究。
来自一家商业养殖场、已知感染几种常见猪病原体的猪。
将7至10日龄的仔猪断奶并与原养殖场隔离，与场内断奶并饲养的同窝对照仔猪（14至17日龄）进行比较。从仔猪7至10日龄开始，每隔14天测量一次猪的体重，并分离微生物菌群，持续84天。
50日龄时，隔离饲养的早期断奶仔猪平均体重为23.7千克，而对照仔猪平均体重为12.5千克。从隔离饲养的早期断奶仔猪中分离出多杀性巴氏杆菌的数量少于对照仔猪。在对照仔猪中检测到猪肺炎支原体感染迹象，而在隔离饲养的早期断奶仔猪中未检测到。两组均未检测到胸膜肺炎放线杆菌产后早期垂直传播的临床、血清学或细菌学迹象。
7至10日龄断奶并在场外隔离饲养仔猪可预防猪肺炎支原体的垂直传播，无需使用药物。尽管未对使用药物的对照组进行比较，但该猪群的结果表明，在隔离早期断奶计划中，使用抗生素并非疾病控制的最重要因素。在疾病控制方案中尽量减少抗生素的使用可降低成本，同时无需使用超说明书用药。
