Fontaine M, McSherry B J, Valli V E
Can J Comp Med. 1977 Apr;41(2):202-5.
An evaluation was made of a rapid semiautomated method for determining fibrinogen level in swine plasma. This method, referred to as thrombin time method or fibrometer method, is based on the principle that when thrombin is added to suitably diluted plasma, the time of clotting is linearly related to the fibrinogen concentration. The linear regression model for the standard curve prepared using swine plasma had an r value of 0.998. A comparison between the fibrometer and the Grannis methods done on 189 swine plasma samples showed good correlation between these two mehtods (r value 0.847). It was concluded that although the fibrometer method may not be as precise as the Grannis method, it would still be acceptable for clinical use in swine.
对一种用于测定猪血浆中纤维蛋白原水平的快速半自动方法进行了评估。这种方法被称为凝血酶时间法或纤维蛋白原测定仪法，其原理是当将凝血酶添加到适当稀释的血浆中时，凝血时间与纤维蛋白原浓度呈线性相关。使用猪血浆制备的标准曲线的线性回归模型的r值为0.998。对189份猪血浆样本进行的纤维蛋白原测定仪法和格兰尼斯法之间的比较显示，这两种方法之间具有良好的相关性（r值为0.847）。得出的结论是，尽管纤维蛋白原测定仪法可能不如格兰尼斯法精确，但对于猪的临床应用来说仍然是可以接受的。
