Pineros O E, Cohen E J, Rapuano C J, Laibson P R
Cornea Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pa., USA.
Arch Ophthalmol. 1996 May;114(5):525-8. doi: 10.1001/archopht.1996.01100130517002.
To determine the outcome and refractive status after triple and nonsimultaneous procedures for Fuchs' endothelial dystrophy and cataract.
Records of 236 patients with Fuchs' endothelial dystrophy who were examined during 1988 were reviewed retrospectively.
Group 1 consisted of 93 patients who had triple procedures (penetrating keratoplasty, extracapsular cataract extraction, and posterior chamber intraocular lens implantation); group 2 consisted of 32 patients who had nonsimultaneous procedures (penetrating keratoplasty followed by extracapsular cataract extraction and posterior chamber intraocular lens implantation). Variables in the first eye that had surgery for each patient were compared between the groups by means of unpaired t tests and Fisher's exact test.
Mean follow-up after undergoing transplantation was 6 years in group 1 and 8 years in group 2. Clear grafts were obtained in 89 (96%) of eyes of group 1 and in 29 (91%) of eyes in group 2 (P = .37). A best-corrected visual acuity of 20/40 or better was achieved in 60 (65%) of eyes in group 1 and in 21 (66%) of eyes in group 2. Refractive errors within 2 diopters of emmetropia were found in 37 (42%) of eyes in group 1 and in 15 (48%) of eyes in group 2 (P = .51). Mean refractive cylinder was 3.9 diopters in group 1 and 4.1 diopters in group 2 (P = .67).
There was no statistically significant difference in the outcome and refractive status after triple and nonsimultaneous procedures. To avoid increased cost and delay in visual rehabilitation, we recommend a triple procedure for patients with Fuchs' endothelial dystrophy and visually significant cataracts.
确定针对富克斯内皮营养不良和白内障的三联手术及非同时手术的术后效果和屈光状态。
回顾性分析了1988年检查的236例富克斯内皮营养不良患者的记录。
第1组由93例行三联手术(穿透性角膜移植术、囊外白内障摘除术和后房型人工晶状体植入术)的患者组成;第2组由32例行非同时手术(先进行穿透性角膜移植术,随后进行囊外白内障摘除术和后房型人工晶状体植入术)的患者组成。通过非配对t检验和费舍尔精确检验对两组中每位患者接受手术的第一眼的变量进行比较。
第1组移植术后平均随访6年,第2组为8年。第1组89只眼(96%)获得了透明植片,第2组29只眼(91%)获得了透明植片(P = 0.37)。第1组60只眼(65%)和第2组21只眼(66%)的最佳矫正视力达到20/40或更好。第1组37只眼(42%)和第2组15只眼(48%)的屈光不正度数在正视眼2屈光度范围内(P = 0.51)。第1组平均屈光柱镜度数为3.9屈光度,第2组为4.1屈光度(P = 0.67)。
三联手术和非同时手术在术后效果和屈光状态方面无统计学显著差异。为避免费用增加和视觉康复延迟,我们建议对患有富克斯内皮营养不良且白内障具有明显视觉影响的患者采用三联手术。