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[快速气相色谱法测定人血浆和血液透析液中的醋酸盐(作者译)]

[Rapid gas chromatographic method for determination of acetate in human plasma and hemodialysis baths (author's transl)].

作者信息

Desch G, Descomps B

出版信息

Clin Chim Acta. 1977 Apr 15;76(2):193-204. doi: 10.1016/0009-8981(77)90096-1.

Abstract

A rapid and sensitive method for acetate determination in human plasma and in hemodialysis baths (dialysates) is going to become necessary owing to the extensive using of sodium acetate solution in hemodialysis. The gas chromatographic method reported here allows, in about 35 minutes, the precise and reproducible measurement of acetate concentrations ranging from 0.2 to 20 mmol/1. This method can be used to investigate the kinetics of acetate concentration variations in the blood of patients undergoing hemodialysis with sodium acetate solution and to evaluate the amount of acetate absorbed during this treatment.

摘要

由于醋酸钠溶液在血液透析中的广泛应用,一种快速、灵敏地测定人血浆和血液透析浴(透析液)中醋酸盐的方法将变得十分必要。本文报道的气相色谱法能够在约35分钟内精确且可重复地测量浓度范围为0.2至20 mmol/1的醋酸盐浓度。该方法可用于研究使用醋酸钠溶液进行血液透析的患者血液中醋酸盐浓度变化的动力学,并评估该治疗过程中吸收的醋酸盐量。

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