Pervikov Iu V, Fafana Ia, Koldoba L G
Vopr Virusol. 1978 Jul-Aug(4):470-3.
The intratypic antigenic differentiation of poliovirus strains isolated from sick or healthy children in Mali in 1975-1976 was performed. The method is based on the use of cross-adsorbed sera in the neutralization tests in which the virus is titrated by the plaque procedure or by the cytopathic effect. All the examined strains of serologic types I, II, and III were distinguished by the antigenic structure from the vaccine strains and were classified as "wild". Quantitative differences in the antigenic structure of type I strains isolated in different towns of Mali were found.
对1975 - 1976年从马里患病或健康儿童中分离出的脊髓灰质炎病毒株进行了型内抗原分化研究。该方法基于在中和试验中使用交叉吸附血清，其中病毒通过空斑法或细胞病变效应进行滴定。所有检测的血清1型、2型和3型毒株在抗原结构上与疫苗株不同，被归类为“野生型”。发现了在马里不同城镇分离出的1型毒株在抗原结构上的定量差异。
