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新转诊至心脏病专家处的胸痛患者中食管疾病的患病率。

Prevalence of esophageal disorders in patients with chest pain newly referred to the cardiologist.

作者信息

Voskuil J H, Cramer M J, Breumelhof R, Timmer R, Smout A J

机构信息

Department of Gastroenterology, St. Antonius Hospital, Nieuwegein, the Netherlands.

出版信息

Chest. 1996 May;109(5):1210-4. doi: 10.1378/chest.109.5.1210.

Abstract

STUDY OBJECTIVE

The prevalence of esophageal disorders (dysmotility and/or gastroesophageal reflux) in patients with chest pain newly referred to a cardiologic clinic is unknown. The aims of our study were to investigate the prevalence of esophageal abnormalities in these patients and to assess the value of medical history in predicting the origin of the patient's chest pain.

DESIGN

We evaluated 28 consecutive patients who were newly referred to the cardiologist because of angina-like chest pain. Patients with evidence of severe myocardial ischemia were excluded. Cardiologic evaluation included medical history, physical examination, ECG, and exercise testing; further cardiologic workup was carried out only when considered necessary. Gastroenterologic evaluation consisted of medical history, esophageal manometry, endoscopy, and 24-h ambulatory monitoring of esophageal pH and pressure.

MEASUREMENTS AND RESULTS

In five patients a diagnosis of ischemic coronary artery disease was made. In only two of these five patients, the cardiologic history strongly suggested a cardiac origin of the pain. Twelve patients had a pathologic 24-h pH profile, four of whom also had reflux esophagitis. Ten patients had symptomatic reflux. In only three of these ten patients, the history was judged to be indicative of an esophageal origin of the chest pain. No motility disorders were found.

CONCLUSIONS

Thirty-six percent of the patients with chest pain newly referred to a cardiologic out-patient clinic have symptomatic gastroesophageal reflux. Neither cardiologic nor gastroenterologic history data have a high predictive value with respect to the origin of the chest pain.

摘要

研究目的

新转诊至心脏病诊所的胸痛患者中食管疾病(动力障碍和/或胃食管反流)的患病率尚不清楚。我们研究的目的是调查这些患者中食管异常的患病率,并评估病史对预测患者胸痛来源的价值。

设计

我们评估了28例因心绞痛样胸痛新转诊至心脏病专家处的患者。排除有严重心肌缺血证据的患者。心脏评估包括病史、体格检查、心电图和运动试验;仅在认为必要时才进行进一步的心脏检查。胃肠病学评估包括病史、食管测压、内镜检查以及食管pH值和压力的24小时动态监测。

测量与结果

5例患者被诊断为缺血性冠状动脉疾病。在这5例患者中,只有2例的心脏病史强烈提示疼痛起源于心脏。12例患者24小时pH值曲线异常,其中4例还患有反流性食管炎。10例患者有症状性反流。在这10例患者中,只有3例的病史被判定提示胸痛起源于食管。未发现动力障碍。

结论

新转诊至心脏病门诊的胸痛患者中,36%有症状性胃食管反流。心脏病史和胃肠病学史数据对于胸痛的来源均没有很高的预测价值。

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