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儿童经皮内镜下胃造口术:对胃食管反流的影响

Percutaneous endoscopic gastrostomy in children: influence on gastroesophageal reflux.

作者信息

Launay V, Gottrand F, Turck D, Michaud L, Ategbo S, Farriaux J P

机构信息

Department of Pediatric Gastroenterology, University Hospital, Lille, France.

出版信息

Pediatrics. 1996 May;97(5):726-8.

PMID:8628615
Abstract

OBJECTIVE

Few data exist in the literature about the relationship between percutaneous endoscopic gastrostomy (PEG) and gastroesophageal reflux (GER) in children, and the data that do exist are contradictory. The aim of the present study was to evaluate the effect of PEG on GER.

METHODS

Twenty children underwent PEG for enteral nutrition. They were 55 +/- 55 months old and weighed 13 +/- 10 kg. A pH study was performed before and after PEG without treatment when GER status was unknown (n = 10) or under treatment (n = 10) if previous GER was demonstrated. In these cases, the pH study was performed under the same treatment before and after PEG.

RESULTS

Six pH studies had abnormal results before PEG. After PEG, the GER of these 6 children significantly improved after the treatment was intensified (n = 50 or spontaneously normalized (n = 1). Results of 13 pH studies that were previously normal remained normal. Only one child with a normal reflux index before PEG had GER after it. For the 20 children, the mean reflux index did not change significantly after PEG (5.5% vs 5.6%).

CONCLUSION

Contrary to surgical gastrostomy, PEG does not worsen GER. Therefore, GER is not a contraindication to PEG.

摘要

目的

关于儿童经皮内镜下胃造口术(PEG)与胃食管反流(GER)之间关系的文献资料较少,且现有数据相互矛盾。本研究的目的是评估PEG对GER的影响。

方法

20名儿童接受PEG进行肠内营养。他们年龄为55±55个月,体重为13±10千克。当GER状态未知时(n = 10),在PEG前后未进行治疗的情况下进行pH研究;如果之前已证实存在GER,则在治疗期间(n = 10)进行PEG前后的pH研究。在这些情况下,pH研究在PEG前后的相同治疗下进行。

结果

6次pH研究在PEG前结果异常。PEG后,这6名儿童中的GER在强化治疗后(n = 5)显著改善或自发恢复正常(n = 1)。之前正常的13次pH研究结果仍保持正常。只有一名PEG前反流指数正常的儿童在PEG后出现GER。对于这20名儿童,PEG后平均反流指数无显著变化(5.5%对5.6%)。

结论

与手术胃造口术不同,PEG不会加重GER。因此,GER不是PEG的禁忌证。

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