Khairullah N S, Lam S K
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Southeast Asian J Trop Med Public Health. 1995 Jun;26(2):263-7.
In 1990 and 1991, six laboratories located in the WHO Western Pacific Region (WPR) and South East Asian Region (SEAR) were selected, based on their experience in the immunofluorescence antibody technique (IFAT), to participate in the evaluation of a WHO monoclonal antibody (Mab) kit to detect respiratory syncytial (RS) virus, influenza A virus, influenza B virus, parainfluenza virus and adenovirus. Despite differences in the initial standardization procedures, the WHO monoclonal antibodies were found to be of high quality, sensitivity and specificity when tested on clinical specimens. The constant supply of affordable high quality reagents from WHO would enable their use in clinical virological laboratories in the developing countries as well as promote the utilization of IFAT as an adjunct to cell culture isolation in the diagnosis of acute respiratory viral infections.
1990年和1991年，根据其在免疫荧光抗体技术（IFAT）方面的经验，选择了位于世界卫生组织西太平洋区域（WPR）和东南亚区域（SEAR）的六个实验室，参与评估世界卫生组织用于检测呼吸道合胞（RS）病毒、甲型流感病毒、乙型流感病毒、副流感病毒和腺病毒的单克隆抗体（Mab）试剂盒。尽管初始标准化程序存在差异，但在临床标本上进行测试时，发现世界卫生组织的单克隆抗体具有高质量、高灵敏度和高特异性。世界卫生组织持续供应价格合理的高质量试剂，将使其能够在发展中国家的临床病毒学实验室中使用，并促进将免疫荧光抗体技术用作细胞培养分离的辅助手段，以诊断急性呼吸道病毒感染。
