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克罗恩病患者中模仿原发性结肠癌的髓外浆细胞瘤。病例报告及文献综述。

Extramedullary plasmacytoma mimicking primary colonic carcinoma in a patient with Crohn's disease. Case report and literature review.

作者信息

Ligato S, El-Naggar A, Cleary K R, Manning J

机构信息

Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, USA.

出版信息

Arch Pathol Lab Med. 1996 Mar;120(3):279-82.

PMID:8629905
Abstract

We present the case of a 45-year-old man who underwent segmental resection for what was considered clinically to be a primary colonic carcinoma. Histopathologic evaluation revealed the tumor to be a malignant plasmacytoma of the colon. Additionally, the entire segment of distal ileum and colon was involved by an inflammatory process with the features of Crohn's disease, accompanied by focal glandular dyplasia of the colonic mucosa. This case reemphasizes that plasmacytoma of the colon can closely mimic carcinoma of the colon in its presentation. The association between plasmacytoma of the colon and Crohn's disease has not, to our knowledge, been described previously.

摘要

我们报告一例45岁男性患者,其接受了节段性切除术,临床诊断为原发性结肠癌。组织病理学评估显示,该肿瘤为结肠恶性浆细胞瘤。此外,回肠末端和结肠的整个节段均出现了具有克罗恩病特征的炎症过程,并伴有结肠黏膜局灶性腺上皮发育异常。该病例再次强调,结肠浆细胞瘤在临床表现上可酷似结肠癌。据我们所知,此前尚未有结肠浆细胞瘤与克罗恩病关联的相关描述。

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