Jagminas L, Silverman R A
Rhode Island Hospital Department of Emergency Medicine, Providence 02903, USA.
Am J Emerg Med. 1996 Jan;14(1):53-6. doi: 10.1016/S0735-6757(96)90016-9.
This case of Boerhaave's Syndrome had several unusual features including a delayed presentation and right-sided esophageal perforation. The patient's initial episode of hematemesis may have been caused by a small mucosal laceration in the area of the Barrett's lesion that later ruptured. On the other hand, if initially there was an esophageal rupture, it did not violate the parietal pleura or mediastinum. The overlying pleura remained intact until digested by gastric contents, thereby causing a right-sided hydropneumo thorax and a marked increase in symptoms, which promoted the patient to come to the ED. Because the patient initially appeared stable and had a history of emesis 4 days before presentation, and because an initial chest X-ray interpretation overlooked the right-sided apical pneumothorax, Boerhaave's Syndrome was not considered initially. Aspiration pneumonia, pancreatitis, alcoholic gastritis, or active peptide ulcer disease were in our initial differential. It was only after the repeat chest X-ray, which more obviously showed the pneumothorax, and insertion of the chest tube that the correct diagnosis was made. Had the pneumothorax not been overlooked initially, the diagnosis may have been made earlier. It is apparent from this case and a review of the literature that Boerhaave's Syndrome is an uncommon clinical entity and has varying modes of presentation, making the diagnosis a difficult clinical challenge. Boerhaave's Syndrome should be considered in all ill-appearing patients presenting with the combination of gastrointestinal and respiratory complaints. The single most important test may be the upright chest X-ray. However, if it is normal, and there is a high index of suspicion, esophagograms and or chest CT may be required to demonstrate the lesion. Because survival is directly related to the time to diagnosis and treatment, a high clinical suspicion can decrease the substantial morbidity and mortality associated with Boerhaave's Syndrome.
该例Boerhaave综合征有几个不寻常的特征,包括就诊延迟和右侧食管穿孔。患者最初的呕血可能是由巴雷特病变区域的小黏膜撕裂伤引起的,该撕裂伤后来破裂。另一方面,如果最初存在食管破裂,它并未侵犯壁层胸膜或纵隔。覆盖的胸膜保持完整,直到被胃内容物消化,从而导致右侧液气胸并使症状显著加重,促使患者前往急诊科就诊。由于患者最初看起来情况稳定,且在就诊前4天有呕吐史,并且最初的胸部X线检查结果忽略了右侧肺尖气胸,因此最初未考虑Boerhaave综合征。我们最初的鉴别诊断包括吸入性肺炎、胰腺炎、酒精性胃炎或活动性肽溃疡病。直到重复胸部X线检查更明显地显示出气胸并插入胸管后,才做出正确诊断。如果气胸最初没有被忽略,诊断可能会更早做出。从该病例以及文献回顾中可以明显看出,Boerhaave综合征是一种不常见的临床实体,有多种表现形式,这使得诊断成为一项困难的临床挑战。对于所有出现胃肠道和呼吸道症状的病情不佳的患者,都应考虑Boerhaave综合征。最重要的单项检查可能是立位胸部X线检查。然而,如果结果正常,但怀疑指数较高,则可能需要进行食管造影和/或胸部CT来显示病变。由于生存率与诊断和治疗时间直接相关,高度的临床怀疑可以降低与Boerhaave综合征相关的高发病率和死亡率。