肺原发性滑膜肉瘤中的（X；18）易位
Translocation (X;18) in primary synovial sarcoma of the lung.
作者信息
Roberts C A, Seemayer T A, Neff J R, Alonso A, Nelson M, Bridge J A
机构信息
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198-3135, USA.
出版信息
Cancer Genet Cytogenet. 1996 May;88(1):49-52. doi: 10.1016/0165-4608(95)00298-7.
Primary sarcomas of the lung are extremely rare. Among the most common to occur in this location are leiomyosarcoma, fibrosarcoma, and hemangiopericytoma. Many difficulties are encountered when establishing these sarcoma diagnoses, or one of another pathologic type, because of overlapping histologic features and morphologic similarities between primary and metastatic lesions. In this study, the diagnosis of a primary monophasic synovial sarcoma of the lung was aided by the observation of the X;18 translocation characteristic of this neoplasm. To the best of our knowledge, this is the first cytogenetic report of a primary pulmonary synovial sarcoma.
原发性肺肉瘤极为罕见。该部位最常见的肉瘤包括平滑肌肉瘤、纤维肉瘤和血管外皮细胞瘤。由于原发性和转移性病变之间存在组织学特征重叠和形态学相似性，在确立这些肉瘤诊断或其他病理类型的诊断时会遇到许多困难。在本研究中，通过观察该肿瘤特有的X;18易位，辅助诊断了一例原发性单相性肺滑膜肉瘤。据我们所知，这是原发性肺滑膜肉瘤的首例细胞遗传学报告。
Zotero 插件