Solomon J, Bradwin G, Cocchia M A, Coffey D, Condon T, Garrity W, Grieco W
Horm Metab Res. 1977 Mar;9(2):152-6. doi: 10.1055/s-0028-1093566.
Observation on body weight gain, blood glucose levels, and responses to a glucose challenge in ob/ob mice adrenalectomized at five months of age, demonstrate that removal of the adrenals of older mice retains the potential to lower serum glucose levels and depress body weight gain seen in young ob/ob mice adrenalectomized at two months of age. These findings suggest that the adrenals continue to play a role in body weight gain and hyperglycemia of the ob/ob mouse up to five months of age.
对5月龄切除肾上腺的ob/ob小鼠的体重增加、血糖水平及葡萄糖耐量反应的观察表明，切除老年小鼠的肾上腺仍有可能降低血清葡萄糖水平，并抑制2月龄切除肾上腺的年轻ob/ob小鼠的体重增加。这些发现提示，肾上腺在ob/ob小鼠5月龄前的体重增加和高血糖中持续发挥作用。
