来自鸡胗角质化膜-腺层的一种新磷脂的结构。

The structure of a new phospholipid from the koilin-glandular layer of chicken gizzard.

作者信息

Grujić-Injac B, Dimitrijević M, Lajsić S, Stefanović D, Mićović I

出版信息

Hoppe Seylers Z Physiol Chem. 1977 Apr;358(4):499-504. doi: 10.1515/bchm2.1977.358.1.499.

DOI:10.1515/bchm2.1977.358.1.499

Abstract

A new phospholipid (Mr = 653; C32H64NO10P; [alpha]22D: - 24) was isolated from the keratinoidal layer of chicken gizzard. After acid hydrolysis the following products were identified: a C22-saturated aldehyde, sn-glycerol 3-phosphate, ethanolamine and D(-)-ribose. The substance is stable to alkali, it has saturated character, and after hydrolysis with CH3OH/HCI, yields only C22-dimethyl acetal. It contains a free NH2 group, and methylation produces 2,3,4-tri-O-methyl-D-ribose. The probable structure of the isolated phospholipid is proposed as 1,2-O-do-cosylidene-sn-glycero-3-phospho-(1 inch-ribosyl)-ethanolamine.

摘要

从鸡胗角蛋白层中分离出一种新的磷脂（相对分子质量=653；C32H64NO10P；[α]22D：-24）。酸水解后鉴定出以下产物：一种C22饱和醛、sn-甘油3-磷酸、乙醇胺和D（-）-核糖。该物质对碱稳定，具有饱和特性，用CH3OH/HCl水解后，仅产生C22二甲基缩醛。它含有一个游离NH2基团，甲基化产生2,3,4-三-O-甲基-D-核糖。所分离磷脂的可能结构被推测为1,2-O-二十二烷基叉-sn-甘油-3-磷酸-（1'-核糖基）-乙醇胺。