乳酸链球菌素可刺激金黄色葡萄球菌和大肠杆菌的耗氧量。
Nisin stimulates oxygen consumption by Staphylococcus aureus and Escherichia coli.
作者信息
Carneiro de Melo A M, Cook G M, Miles R J, Poole R K
机构信息
Division of Life Sciences, King's College London, United Kingdom.
出版信息
Appl Environ Microbiol. 1996 May;62(5):1831-4. doi: 10.1128/aem.62.5.1831-1834.1996.
Abstract
Nisin stimulated oxygen consumption by nongrowing, glucose-metabolizing Staphylococcus aureus and Escherichia coli cells, indicating a protonophore mode of action. A similar stimulation in E. coli cells osmotically stressed to disrupt the outer cell membrane confirmed the cytoplasmic membrane as the site of nisin action and showed that nisin uptake was not prevented by the outer membrane.
摘要
乳酸链球菌素刺激了不生长的、进行葡萄糖代谢的金黄色葡萄球菌和大肠杆菌细胞的氧气消耗，这表明其作用方式为质子载体模式。对经渗透压胁迫以破坏外细胞膜的大肠杆菌细胞的类似刺激，证实了细胞质膜是乳酸链球菌素的作用位点，并表明外膜不会阻止乳酸链球菌素的摄取。
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