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乳酸链球菌素可刺激金黄色葡萄球菌和大肠杆菌的耗氧量。

Nisin stimulates oxygen consumption by Staphylococcus aureus and Escherichia coli.

作者信息

Carneiro de Melo A M, Cook G M, Miles R J, Poole R K

机构信息

Division of Life Sciences, King's College London, United Kingdom.

出版信息

Appl Environ Microbiol. 1996 May;62(5):1831-4. doi: 10.1128/aem.62.5.1831-1834.1996.

DOI:10.1128/aem.62.5.1831-1834.1996
PMID:8633884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC167960/
Abstract

Nisin stimulated oxygen consumption by nongrowing, glucose-metabolizing Staphylococcus aureus and Escherichia coli cells, indicating a protonophore mode of action. A similar stimulation in E. coli cells osmotically stressed to disrupt the outer cell membrane confirmed the cytoplasmic membrane as the site of nisin action and showed that nisin uptake was not prevented by the outer membrane.

摘要

乳酸链球菌素刺激了不生长的、进行葡萄糖代谢的金黄色葡萄球菌和大肠杆菌细胞的氧气消耗，这表明其作用方式为质子载体模式。对经渗透压胁迫以破坏外细胞膜的大肠杆菌细胞的类似刺激，证实了细胞质膜是乳酸链球菌素的作用位点，并表明外膜不会阻止乳酸链球菌素的摄取。

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本文引用的文献

1
Mode of Action of Nisin Z against Listeria monocytogenes Scott A Grown at High and Low Temperatures.尼辛 Z 对高温和低温生长的单核细胞增生李斯特氏菌的作用模式。
Appl Environ Microbiol. 1994 Jun;60(6):1962-8. doi: 10.1128/aem.60.6.1962-1968.1994.
2
Common mechanistic action of bacteriocins from lactic Acid bacteria.乳酸菌细菌素的常见作用机制。
Appl Environ Microbiol. 1993 Sep;59(9):3003-10. doi: 10.1128/aem.59.9.3003-3010.1993.
3
Effect of oral neomycin on normal intestinal flora of dogs and man.
Proc Soc Exp Biol Med. 1952 Feb;79(2):335-8. doi: 10.3181/00379727-79-19369.
4
In vitro pore-forming activity of the lantibiotic nisin. Role of protonmotive force and lipid composition.羊毛硫抗生素乳链菌肽的体外成孔活性。质子动力和脂质组成的作用。
Eur J Biochem. 1993 Mar 1;212(2):417-22. doi: 10.1111/j.1432-1033.1993.tb17677.x.
5
Phosphoenolpyruvate:carbohydrate phosphotransferase systems of bacteria.细菌的磷酸烯醇丙酮酸：碳水化合物磷酸转移酶系统
Microbiol Rev. 1993 Sep;57(3):543-94. doi: 10.1128/mr.57.3.543-594.1993.
6
Correlation of bioenergetic parameters with cell death in Listeria monocytogenes cells exposed to nisin.暴露于乳链菌肽的单核细胞增生李斯特氏菌细胞中生物能量参数与细胞死亡的相关性
Appl Environ Microbiol. 1994 Nov;60(11):4186-8. doi: 10.1128/aem.60.11.4186-4188.1994.
7
Mechanistic studies of lantibiotic-induced permeabilization of phospholipid vesicles.羊毛硫抗生素诱导磷脂囊泡通透性增加的机制研究。
Biochemistry. 1995 Feb 7;34(5):1606-14. doi: 10.1021/bi00005a017.
8
Mechanisms of active transport in isolated bacterial membrane vesicles. 18. The mechanism of action of carbonylcyanide m-chlorophenylhydrazone.分离的细菌膜囊泡中主动运输的机制。18. 间氯苯腙羰基氰化物的作用机制。
Arch Biochem Biophys. 1974 Jan;160(1):215-22. doi: 10.1016/s0003-9861(74)80028-7.
9
Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles.肽抗生素乳链菌肽的作用模式及其对全细胞膜电位以及细胞质膜和人工膜囊泡的影响。
Antimicrob Agents Chemother. 1985 May;27(5):841-5. doi: 10.1128/AAC.27.5.841.
10
Quantitative relationship between protonophoric and uncoupling activities of substituted phenols.取代酚的质子载体活性与解偶联活性之间的定量关系。
Biochim Biophys Acta. 1987 Apr 15;891(2):194-204. doi: 10.1016/0005-2728(87)90011-9.