Cerri R, Pintore G, Dessí G, Asproni B, Piseddu G, Sini S
Istituto di Analitica Farmaceutica, Sassari, Italy.
Farmaco. 1995 Dec;50(12):841-8.
The glycoside fraction of fresh rhizomes from Magydaris pastinacea (Lam.) Paol. was separated from the alcoholic extract using the method of Kobayashi et al. The fraction was found to have six main constituents, the most abundant of which had previously been isolated and identified as 7-O-beta-D-glucopyranosyl-8-(2',3'-dihydroxy-3-methyl-butylcoumarin++ +). The present paper describes the separation and characterization of the other constituents, all with coumarin or furancoumarin structures. Pharmacological experiments to test these compounds as platelet antiaggregants are also reported.
采用小林等人的方法,从Magydaris pastinacea (Lam.) Paol.新鲜根茎的乙醇提取物中分离出糖苷部分。发现该部分有六个主要成分,其中含量最高的成分先前已被分离并鉴定为7-O-β-D-吡喃葡萄糖基-8-(2',3'-二羟基-3-甲基丁基香豆素)。本文描述了其他成分的分离和表征,所有成分均具有香豆素或呋喃香豆素结构。还报道了测试这些化合物作为血小板抗聚集剂的药理实验。