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扩大免疫规划对塞拉利昂西部地区麻疹诱发的感音神经性听力损失的影响。

The impact of the Expanded Programme on Immunisation on measles-induced sensorineural hearing loss in the western area of Sierra Leone.

作者信息

Wright D O, Leigh B

机构信息

Department of Otolaryngology, Connaught Hospital, Freetown, Sierra Leone.

出版信息

West Afr J Med. 1995 Oct-Dec;14(4):205-9.

PMID:8634225
Abstract

Measles was found to be responsible for 46.1% of acquired sensorineural hearing loss in children in a study conducted in the western area of Sierra Leone between 1975 to 1985. 125 children with acquired sensorineural hearing loss were seen and investigated in this study, which was conducted to determine the impact of the Expanded Programme on Immunisation and measles-induced hearing loss. 17 children had sensorineural hearing loss consequent to an attack of measles. A progressive drop in the number of cases seen from 6 in 1986 to 0 in 1989 was observed. During the same period the measles immunisation coverage in Sierra Leone increased from 21% in 1986 to 75% in 1990. Given that measles and some other causes of sensorineural hearing loss were preventable, it was hypothesised that lower incidence of these diseases would result in lower rates of acquired sensorineural hearing loss. This study demonstrated an inverse relationship between the incidence of measles induced sensorineural hearing loss and the increased immunisation coverage when Universal Child Immunisation (UCI) was attained in 1990.

摘要

在1975年至1985年于塞拉利昂西部地区开展的一项研究中,发现麻疹是导致儿童后天性感音神经性听力损失的原因,占比46.1%。该研究旨在确定扩大免疫规划和麻疹所致听力损失的影响,共诊治并调查了125名后天性感音神经性听力损失儿童。其中17名儿童因麻疹发作而出现感音神经性听力损失。观察到病例数从1986年的6例逐渐下降至1989年的0例。同一时期,塞拉利昂的麻疹免疫接种覆盖率从1986年的21%增至1990年的75%。鉴于麻疹和其他一些导致感音神经性听力损失的病因是可以预防的,因此推测这些疾病发病率降低会使后天性感音神经性听力损失率下降。该研究表明,1990年实现儿童全面免疫接种(UCI)后,麻疹所致感音神经性听力损失发病率与免疫接种覆盖率提高之间存在负相关关系。

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