Department of Ear, Nose and Throat, Ekiti State University Teaching Hospital, Ado Ekiti, Ekiti State, Nigeria.
Department of Paediatrics, Ekiti State University Teaching Hospital, Ado Ekiti, Ekiti State, Nigeria.
Pan Afr Med J. 2021 Jan 28;38:98. doi: 10.11604/pamj.2021.38.98.21438. eCollection 2021.
a strong need exists for the knowledge of aetiologies of diseases as this will guide the clinicians on the strategies for their treatment and prevention. In this study, we determined the aetiologies of profound bilateral sensorineural hearing loss (pbSNHL) with a view to provide the relevant data needed for preventive and therapeutic intervention among children in Ekiti State, South Western Nigeria.
medical records of children with pbSNHL seen over a ten-year period were analysed.
in all, records of 142 children with pbSNHL were analysed. The results showed spectrum of aetiologies that were similar to those reported decades ago with the 'unknown' assuming a recurring decimal. Of the known (acquired) cases, measles takes up the largest 'chunk' with a prevalence of 45.8%. Twenty-eight (32.2%) of those with febrile illnesses had treated their fever with ototoxic antibiotics. Late diagnosis was characteristic of the pbSNHL.
this study shows that there hasn't been any significant shift in the common causes of pbSNHL. Of great concern is the persistence of the 'unknown' causes which assumes a recurring decimal in this and previous studies. Also worrisome is the high prevalence of measles-induced pbSNHL despite the availability of anti-measles vaccine. We therefore suggest effective immunization against measles and other vaccine-preventable causes of pbSNHL. The need for intensive research on the unknown causes of pbSNHL is hereby stressed. Also recommended is routine hearing assessment for survivors of febrile conditions so as to detect, if any, hearing loss promptly.
了解疾病的病因对于临床医生制定治疗和预防策略非常重要。本研究旨在确定导致深度双侧感音神经性听力损失(pbSNHL)的病因,为尼日利亚西南部埃基提州儿童提供预防和治疗干预所需的相关数据。
分析了过去十年中患有 pbSNHL 的儿童的病历记录。
共分析了 142 名患有 pbSNHL 的儿童的记录。结果显示,病因谱与几十年前报告的相似,“未知”病因反复出现。在已知(后天)病例中,麻疹占比最大,为 45.8%。28 名(32.2%)有发热病史的儿童在发热时使用了耳毒性抗生素。pbSNHL 的诊断通常较晚。
本研究表明,pbSNHL 的常见病因没有明显变化。令人担忧的是,“未知”病因仍然存在,这在本研究和之前的研究中都反复出现。此外,尽管有麻疹疫苗,但麻疹引起的 pbSNHL 仍很普遍,这也令人担忧。因此,我们建议针对麻疹和其他可通过疫苗预防的 pbSNHL 病因进行有效免疫接种。强调需要对 pbSNHL 的未知病因进行深入研究。还建议对发热疾病的幸存者进行常规听力评估,以便及时发现任何听力损失。