Loosmore S M, Shortreed J M, Coleman D C, England D M, Klein M H
Connaught Centre for Biotechnology Research, North York, Ontario, Canada.
Gene. 1996 Feb 22;169(1):137-8. doi: 10.1016/0378-1119(95)00808-x.
The genes (dms) encoding the dimethylsulfoxide reductase protein complex have been cloned and sequenced from Haemophilus influenzae (Hi) type b (Hib) strain Eagan. The Hib dms genes are arranged as an operon whose genomic organization is similar to that of the Escherichia coli (Ec) dmsABC operon. The deduced Hib DmsA, and DmsB and DmsC amino-acid sequences are highly homologous to their Ec counterparts and nearly identical to the recently published sequences of the Hi type-d strain Rd Dms proteins. Hi dimethylsulfoxide reductase appears to be a new member of the superfamily of oxidoreductase enzymes.
编码二甲基亚砜还原酶蛋白复合体的基因(dms)已从b型流感嗜血杆菌(Hi)Eagan菌株中克隆并测序。b型流感嗜血杆菌的dms基因排列成一个操纵子,其基因组组织与大肠杆菌(Ec)的dmsABC操纵子相似。推导的b型流感嗜血杆菌DmsA、DmsB和DmsC氨基酸序列与其大肠杆菌对应序列高度同源,并且与最近发表的d型流感嗜血杆菌Rd Dms蛋白序列几乎相同。流感嗜血杆菌二甲基亚砜还原酶似乎是氧化还原酶超家族的一个新成员。