London C A, Dubilzeig R R, Vail D M, Ogilvie G K, Hahn K A, Brewer W G, Hammer A S, O'Keefe D A, Chun R, McEntee M C, McCaw D L, Fox L E, Norris A M, Klausner J S
Department of Medical Sciences School of Veterinary, Medicine, University of Wisconsin, Madison 53706, USA.
J Am Vet Med Assoc. 1996 May 1;208(9):1413-8.
To characterize the frequency, clinical signs, biologic behavior, and response to treatment of tumors of the ear canal in dogs and cats.
Retrospective analysis of medical records.
Medical records of 81 dogs (48 malignant tumors, 33 benign tumors) and 64 cats (56 malignant tumors, 8 benign tumors).
Data were analyzed for cats and dogs with malignant tumors, and risk factors were analyzed for their potential impact on survival time.
Malignant tumor types most commonly reported included ceruminous gland adenocarcinoma, squamous cell carcinoma, and carcinoma of undetermined origin. Median survival time of dogs with malignant aural tumors was > 58 months, whereas that of cats was 11.7 months. A poor prognosis was indicated by extensive tumor involvement (dogs) and by neurologic signs at time of diagnosis, diagnosis of squamous cell carcinoma or carcinoma of undetermined origin, and invasion into lymphatics or blood vessels (cats).
Malignant tumors of the ear canal in dogs and cats have a propensity for local invasion, but tend not to metastasize. Squamous cell carcinoma and carcinoma of undetermined origin were the most locally aggressive tumors. Malignant tumors of the ear canal are best managed by aggressive surgical excision. Radiotherapy may be useful when tumors cannot be completely removed.
描述犬猫耳道肿瘤的发生频率、临床体征、生物学行为及对治疗的反应。
对病历进行回顾性分析。
81只犬（48例恶性肿瘤，33例良性肿瘤）和64只猫（56例恶性肿瘤，8例良性肿瘤）的病历。
对患有恶性肿瘤的猫和犬的数据进行分析，并分析危险因素对生存时间的潜在影响。
最常报告的恶性肿瘤类型包括耵聍腺腺癌、鳞状细胞癌和来源不明的癌。患有恶性耳部肿瘤的犬的中位生存时间>58个月，而猫为11.7个月。广泛的肿瘤累及（犬）以及诊断时出现神经体征、鳞状细胞癌或来源不明的癌的诊断以及侵犯淋巴管或血管（猫）提示预后不良。
犬猫耳道恶性肿瘤有局部侵袭倾向，但往往不发生转移。鳞状细胞癌和来源不明的癌是最具局部侵袭性的肿瘤。耳道恶性肿瘤最好通过积极的手术切除进行治疗。当肿瘤无法完全切除时，放疗可能有用。
