Boné B, Péntek Z, Perbeck L, Veress B
Department of Diagnostic Radiology, Karolinska Institute, Huddinge University Hospital, Sweden.
Acta Radiol. 1997 Jul;38(4 Pt 1):489-96. doi: 10.1080/02841859709174374.
To determine the sensitivity and specificity of X-ray mammography and of MR imaging in 238 consecutively operated breasts, and to correlate the findings to histopathological diagnosis.
Over 15 months, 220 patients scheduled for breast surgery were examined consecutively, before surgery, by means of both mammography and MR imaging. Of the 220 patients, 18 underwent bilateral breast surgery. The entire breast was examined by means of T1-weighted transversal images using a 3D fast low-angle shot (FLASH) sequence. One pre- and 2 post-contrast scans were performed. Each breast was examined by means of mammography and 3 views were applied as routine. All palpable and mammographically suspect lesions were examined on additional images as microfocus magnification or spot compression. The two methods were evaluated independently of each other.
In total, 145 malignant and 93 benign lesions were found at histopathological examination. The sensitivity of mammography was 89% and MR imaging 92%. The specificity was 72% in both methods. When the results of the 2 methods were combined, a sensitivity of 99% and a specificity of 55% was achieved.
Mammography and MR imaging seemed to complement each other to produce a high sensitivity. Unfortunately it is impossible at present to supplement mammography with MR imaging in each patient as a routine owing to the current technical and financial limitations.
确定在238例连续接受手术的乳房中，X线钼靶摄影和磁共振成像（MR成像）的敏感性和特异性，并将结果与组织病理学诊断相关联。
在15个月的时间里，对220例计划接受乳房手术的患者在手术前连续进行钼靶摄影和MR成像检查。在这220例患者中，18例接受了双侧乳房手术。使用三维快速低角度激发（FLASH）序列，通过T1加权横向图像对整个乳房进行检查。进行了一次对比前扫描和两次对比后扫描。通过钼靶摄影对每个乳房进行检查，并按常规拍摄3个视图。所有可触及的和钼靶摄影可疑的病变均在额外的图像上进行检查，如微焦点放大或点压迫。两种方法相互独立评估。
组织病理学检查共发现145个恶性病变和93个良性病变。钼靶摄影的敏感性为89%，MR成像为92%。两种方法的特异性均为72%。当将两种方法的结果结合起来时，敏感性达到99%，特异性达到55%。
钼靶摄影和MR成像似乎相互补充，以产生高敏感性。不幸的是，由于目前的技术和资金限制，目前不可能对每位患者常规用MR成像补充钼靶摄影。
