Cuvelliez S, Rosseel G, Blais D, Salmon Y, Troncy E, Larivière N
Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec, Canada.
Can Vet J. 1995 Oct;36(10):613-8.
Intravenous anesthesia in the horse: Comparison of xylazine-ketamine and xylaxine-tiletamine-zolazepam combinations. Six healthy adult horses were anesthetized twice at random with following intravenous combinations: 1.1 mg/kg of body weight (BW) of xylazine followed by 2.2 mg/kg BW of ketamine (X-K) and 1.1 mg/kg BW of xylazine followed by 1.65 mg/kg BW of tiletamine-zolazepam (X-TZ). The modifications of some cardiorespiratory parameters and the duration of anesthesia were evaluated and compared for the 2 protocols used. Few significant differences were observed between the 2 protocols in regard to the cardiorespiratory parameters measured. The respiratory rate was lower (7 breaths per minute) and the heart rate was higher (34 beats per minute) with the X-TZ combination. The duration of anesthesia with this technique was 33 +/- 3 minutes (X +/- Sx) and longer than with X-K (18 +/- minutes (X +/- Sx)). Superficial analgesia lasted 14,5 +/- 3 minutes with the X-K combination and 31,7 +/- 3,2 minutes for the X-TZ combination. The 2 protocols are associated with a reduction of PaO2.
赛拉嗪-氯胺酮与赛拉嗪-替来他明-唑拉西泮组合的比较。六匹健康成年马被随机用以下静脉组合进行两次麻醉:1.1毫克/千克体重的赛拉嗪,随后是2.2毫克/千克体重的氯胺酮(X-K),以及1.1毫克/千克体重的赛拉嗪,随后是1.65毫克/千克体重的替来他明-唑拉西泮(X-TZ)。对所使用的两种方案,评估并比较了一些心肺参数的变化以及麻醉持续时间。在所测量的心肺参数方面,两种方案之间观察到很少有显著差异。使用X-TZ组合时呼吸频率较低(每分钟7次呼吸),心率较高(每分钟34次心跳)。这种技术的麻醉持续时间为33±3分钟(X±Sx),比X-K组合(18±分钟(X±Sx))更长。X-K组合的浅麻醉持续14.5±3分钟,X-TZ组合为31.7±3.2分钟。两种方案均伴有动脉血氧分压降低。