Flatt J P
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical Center, Worcester 01655, USA.
Int J Obes Relat Metab Disord. 1996 Mar;20 Suppl 2:S1-11.
The degree of replenishment of the body's glycogen stores influences the contribution made by glucose and free fatty acids to the fuel mixed oxidized. The expansion of the adipose tissue mass required to promote fat oxidation to rates commensurate on average with fat intake is therefore influenced not only by the diet's fat content, but by glycogen levels as well. It seems possible that recent changes in the food supply and a further decline in physical activity could have led to some increase in the range within which glycogen levels are habitually maintained, and that this could be a cause for the recent increase in the incidence of obesity noted in many countries.
身体糖原储备的补充程度会影响葡萄糖和游离脂肪酸对混合氧化燃料的贡献。因此，将脂肪氧化促进到与脂肪摄入量平均相当的速率所需的脂肪组织量的增加，不仅受饮食中脂肪含量的影响，还受糖原水平的影响。近期食物供应的变化以及体力活动的进一步减少，似乎有可能导致糖原水平习惯性维持范围有所增加，而这可能是许多国家近期肥胖发病率上升的一个原因。
