Isacsson G, Wasserman D, Bergman U
Department of Clinical Neuroscience and Family Medicine, Karolinska Institute, Huddinge University Hospital, Sweden.
Ann Clin Psychiatry. 1995 Sep;7(3):113-8. doi: 10.3109/10401239509149037.
As part of a WHO project on parasuicide, the medications used for self-poisoning in the Stockholm area were studied. The prescribing rates of the medications were estimated from an independent survey of prescriptions. Anxiolytics, hypnotics, and analgesics were the drugs most commonly used for parasuicide. Related to prescribing rates, antipsychotics and anxiolytics represented an increased risk for parasuicide compared to the average for psychotropics. Analgesics, on the other hand, showed a lower risk for parasuicide. The low number of self-poisonings with antidepressants may reflect that suicidal individuals are seldom prescribed antidepressants and/or that antidepressants actually prevent suicidal acts. As we have shown earlier for completed suicides, underprescribing and therapeutic failure seem to be greater problems with antidepressants than their use for self-poisoning.
作为世界卫生组织关于蓄意自伤项目的一部分，对斯德哥尔摩地区用于自我中毒的药物进行了研究。通过对处方的独立调查估算了这些药物的处方率。抗焦虑药、催眠药和镇痛药是最常用于蓄意自伤的药物。与处方率相关，与精神药物的平均水平相比，抗精神病药和抗焦虑药出现蓄意自伤的风险增加。另一方面，镇痛药出现蓄意自伤的风险较低。使用抗抑郁药进行自我中毒的案例数量较少，这可能反映出自杀个体很少被开具抗抑郁药，和/或抗抑郁药实际上可预防自杀行为。正如我们之前对自杀死亡案例所表明的，抗抑郁药的处方不足和治疗失败似乎比重度抑郁发作时的问题更大。
