Liberman M A, Phillips E H, Carroll B J, Fallas M J, Rosenthal R, Hiatt J
Department of Surgery, Naval Medical Center San Diego, CA 92134, USA.
J Am Coll Surg. 1996 Jun;182(6):488-94.
In the United States of America, approximately 700,000 patients undergo laparoscopic cholecystectomy (LC) each year and at least 10 percent of these patients will have common bile duct stones (CBDS). The purpose of this study was to evaluate patients with choledocholithiasis and compare the economic and clinical results obtained by LC with endoscopic sphincterotomy (ES) with those of LC with laparoscopic transcystic common bile duct exploration (LTCBDE).
From June 1991 to September 1994 patients undergoing LC plus LTCBDE and those undergoing LC plus ES at a single institution were compared where cost data were available. Of the 76 patients with choledocholithiasis, 59 patients underwent LC plus LTCBDE (group 1) and 17 patients underwent LC plus ES (group 2). A subset of group 1 patients undergoing urgent LC plus LTCBDE (group 3) for cholecystitis, cholangitis, or pancreatitis plus laparoscopy were examined separately.
Laparoscopic cholecystectomy plus LTCBDE, whether including all-comers (group 1) or just urgent cases (group 3), was associated with a significantly decreased length of hospital stay (6.1 and 6.9 days, respectively, compared with group 2, 12.4 days) (p < 0.001). The morbidity of patients in group 1 was also markedly lower than for patients in group 2; 12 percent compared with 41 percent, respectively. Patients in group 1 had a significantly decreased cost of hospitalization (+13,151), when compared with patients in group 2 (+18,712) (p = 0.05). This difference is even more pronounced when professional fee reimbursement is considered. The cost of treatment for patients in group 1 was +14,732 compared with +21,125 for patients in group 2 (p < 0.05). The total hospital cost for patients in group 3 was only +13,564 compared with +18,712 for patients in group 2. When professional reimbursement was considered, the cost was +15,150 for patients in group 3 compared with +21,125 for patients in group 2.
Patients undergoing LC plus LTCBDE for CBDS, whether urgently or electively, have markedly decreased morbidity rates, length of hospital stay, and costs when compared with patients undergoing LC plus ES.
在美国,每年约有70万患者接受腹腔镜胆囊切除术(LC),其中至少10%的患者会有胆总管结石(CBDS)。本研究的目的是评估胆总管结石患者,并比较LC联合内镜括约肌切开术(ES)与LC联合腹腔镜经胆囊管胆总管探查术(LTCBDE)的经济和临床结果。
对1991年6月至1994年9月在单一机构接受LC加LTCBDE以及接受LC加ES的患者进行比较,这些患者有可用的成本数据。在76例胆总管结石患者中,59例接受了LC加LTCBDE(第1组),17例接受了LC加ES(第2组)。对第1组中因胆囊炎、胆管炎或胰腺炎加腹腔镜检查而接受紧急LC加LTCBDE的患者子集(第3组)进行单独检查。
腹腔镜胆囊切除术加LTCBDE,无论是包括所有患者(第1组)还是仅紧急病例(第3组),住院时间均显著缩短(分别为6.1天和6.9天,而第2组为12.4天)(p<0.001)。第1组患者的发病率也明显低于第2组患者;分别为12%和41%。与第2组患者(+18,712)相比,第1组患者的住院费用显著降低(+13,151)(p=0.05)。考虑专业费用报销时,这种差异更为明显。第1组患者的治疗费用为+14,732,而第2组患者为+21,125(p<0.05)。第3组患者的总住院费用仅为+13,564,而第2组患者为+18,712。考虑专业报销时,第3组患者的费用为+15,150,而第2组患者为+21,125。
与接受LC加ES的患者相比,接受LC加LTCBDE治疗CBDS的患者,无论紧急与否,发病率、住院时间和费用均显著降低。