格林纳达和特立尼达蝙蝠体内的狂犬病病毒与抗体。

Rabies virus and antibody in bats in Grenada and Trinidad.

作者信息

Price J L, Everard C O

出版信息

J Wildl Dis. 1977 Apr;13(2):131-4. doi: 10.7589/0090-3558-13.2.131.

DOI:10.7589/0090-3558-13.2.131

Abstract

Rabies virus was detected by fluorescent-antibody and mouse inoculation tests in the brain of one bat, Artibeus jamaicensis, collected at La Tante, Grenada on 19 June 1974. No rabies virus was found in the brains and/or salivary glands of 411 other Grenadian bats of 6 species tested, including 56 A. jamaicensis. Rabies neutralizing antibody was detected by the rapid fluorescent focus inhibition test (RFFIT) in 27 of 353 Grenadian bats. Positives occurred in each of the 6 species sampled, with 40.5% prevalence in A. jamaicensis. In 11 of 86 Trinidadian bats of 4 species known to carry rabies, positive sera occurred only in A. jamaicensis (18.6%) and A. lituratus (18.1%). The potential use of the REFIT indetermining rabies activity is discussed.

摘要

1974年6月19日在格林纳达拉坦特采集的一只蝙蝠（即 Jamaicensis 叶鼻蝠）的大脑中，通过荧光抗体和小鼠接种试验检测到了狂犬病病毒。在对包括56只 Jamaicensis 叶鼻蝠在内的6个物种的411只其他格林纳达蝙蝠的大脑和/或唾液腺进行检测时，未发现狂犬病病毒。通过快速荧光灶抑制试验（RFFIT）在353只格林纳达蝙蝠中的27只检测到了狂犬病中和抗体。在采样的6个物种中均出现了阳性结果，其中 Jamaicensis 叶鼻蝠的患病率为40.5%。在已知携带狂犬病的4个物种的86只特立尼达蝙蝠中，有11只检测结果呈阳性，仅在 Jamaicensis 叶鼻蝠（18.6%）和花面叶鼻蝠（18.1%）中出现了阳性血清。文中讨论了快速荧光灶抑制试验在确定狂犬病活动方面的潜在用途。