Kataria Pritam Sureshchandra, Kendre Pradip Piraji, Patel Apurva Ashok, Dalsaniya Sameer
Department of Medical and Paediatric Oncology, GCRI, Ahmedabad, Gujarat, India.
Department of Medical Oncology, GCRI, Ahmedabad, Gujarat, India.
Indian J Dermatol. 2018 Mar-Apr;63(2):182-185. doi: 10.4103/ijd.IJD_7_17.
Prostate adenocarcinoma is a common urologic malignant neoplasm in man. Distant cutaneous metastases (CMs) of prostate carcinoma are extremely rare with a reported incidence of 0.36% and usually they occur late. Clinically, cutaneous metastasis of prostate carcinoma can mimic other skin conditions such as cellulitis, sebaceous cyst, zosteriform lesions, telangectasias, and more, resulting in a poor recognition. Few cases of true cutaneous metastatic prostate carcinoma exist in the literature. We present a case, where the first sign of carcinoma of the prostate was CM over the anterior abdominal wall. Radiological and histopathological confirmation pointed to a diagnosis of carcinoma of the prostate. The patient was treated with orchidectomy and was started on bicalutamide. After 1 month of bicalutamide therapy there was subjective decrease in the size of the metastasis. A high index of suspicion is required while evaluating the different differential diagnoses of this entity particularly in elderly patients.
前列腺腺癌是男性常见的泌尿系统恶性肿瘤。前列腺癌的远处皮肤转移极为罕见，报告发病率为0.36%，且通常发生较晚。临床上，前列腺癌的皮肤转移可类似其他皮肤疾病，如蜂窝织炎、皮脂腺囊肿、带状疱疹样病变、毛细血管扩张等，导致识别困难。文献中真正的皮肤转移性前列腺癌病例很少。我们报告一例，前列腺癌的首个体征是前腹壁皮肤转移。影像学和组织病理学证实为前列腺癌。患者接受了睾丸切除术，并开始服用比卡鲁胺。比卡鲁胺治疗1个月后，转移灶大小主观上有所减小。在评估该疾病的不同鉴别诊断时，尤其是老年患者，需要高度怀疑。
