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本文引用的文献

1
TAC (tetracaine, adrenaline, cocaine): a controversial topical anesthetic for suture of skin lacerations.TAC(丁卡因、肾上腺素、可卡因):一种用于皮肤裂伤缝合的存在争议的局部麻醉剂。
J Emerg Nurs. 1994 Jun;20(3):221-2.
2
Measurement of pain.疼痛的测量。
Lancet. 1974 Nov 9;2(7889):1127-31. doi: 10.1016/s0140-6736(74)90884-8.
3
TAC use and absorption of cocaine in a pediatric emergency department.儿科急诊科中可卡因的TAC使用与吸收情况
Ann Emerg Med. 1990 May;19(5):515-8. doi: 10.1016/s0196-0644(05)82180-8.
4
Comparison of topical tetracaine, adrenaline, and cocaine anesthesia with lidocaine infiltration for repair of lacerations in children.
Ann Emerg Med. 1990 Jan;19(1):63-7. doi: 10.1016/s0196-0644(05)82145-6.
5
A comparison of three formulations of TAC (tetracaine, adrenalin, cocaine) for anesthesia of minor lacerations in children.三种丁卡因(地卡因、肾上腺素、可卡因)制剂用于儿童小伤口麻醉的比较。
Pediatr Emerg Care. 1990 Dec;6(4):266-70. doi: 10.1097/00006565-199012000-00004.
6
Efficacy of tetracaine-adrenaline-cocaine topical anesthetic without tetracaine for facial laceration repair in children.
Pediatrics. 1990 Dec;86(6):856-7.
7
Topical anaesthesia for repair of minor lacerations.用于小伤口修复的局部麻醉。
Arch Dis Child. 1990 Nov;65(11):1272-3; discussion 1274. doi: 10.1136/adc.65.11.1272.
8
Adrenaline-cocaine gel topical anesthetic for dermal laceration repair in children.
Ann Emerg Med. 1992 Dec;21(12):1435-8. doi: 10.1016/s0196-0644(05)80055-1.

儿童裂伤的局部麻醉:一种可接受的方法?

Topical anaesthesia for children's lacerations: an acceptable approach?

作者信息

Kendall J M, Charters A, McCabe S E

机构信息

Accident and Emergency Department, Frenchay Hospital, Bristol, United Kingdom.

出版信息

J Accid Emerg Med. 1996 Mar;13(2):119-22. doi: 10.1136/emj.13.2.119.

DOI:10.1136/emj.13.2.119
PMID:8653235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1342653/
Abstract

OBJECTIVE

To compare the anaesthetic properties of conventional intradermal 1% plain lignocaine with a topical gel preparation of adrenaline (1:2000) and cocaine (4.7%) for use in treatment of children's lacerations.

METHODS

Children aged 3-16 years with lacerations (not of the digits or mucous membranes) were consecutively assigned to receive either adrenaline and cocaine (AC) or lignocaine. Pain scores, as perceived by patients, parents, and staff, were measured conventionally using Wong Baker faces and visual analogue scales on administration of the local anaesthetic and on suturing the wound in the AC group (n = 56) and the lignocaine group (n = 51).

RESULTS

Mean and median pain scores on administration of the anaesthetic in the AC group were significantly lower than in the lignocaine group as perceived by patient (P < 0.001), parent (P < 0.001), and staff (P < 0.001). There was no significant difference in mean and median pain scores between the two groups on suturing the wounds, as perceived by patient, parent and staff. There was a significantly higher number of "failed" anaesthetics (pain scores 8-10) in the lignocaine group (P < 0.01). On direct questioning the overall procedure was considered acceptable by 84.5% of parents in the AC group compared with 61% of parents in the lignocaine group (P < 0.01). There were no significant complications in either group.

CONCLUSIONS

Topical AC should be considered the local anaesthetic of first choice for suturing appropriate children's lacerations.

摘要

目的

比较传统的1% plain利多卡因皮内注射与含肾上腺素(1:2000)和可卡因(4.7%)的局部凝胶制剂用于治疗儿童裂伤时的麻醉特性。

方法

将3至16岁有裂伤(非手指或黏膜裂伤)的儿童连续分配接受肾上腺素和可卡因(AC)或利多卡因。在AC组(n = 56)和利多卡因组(n = 51)中,在给予局部麻醉剂时以及缝合伤口时,由患者、家长和工作人员按常规使用面部表情评分法和视觉模拟评分法测量疼痛评分。

结果

在给予麻醉剂时,患者、家长和工作人员感知到的AC组平均和中位数疼痛评分显著低于利多卡因组(患者:P < 0.001;家长:P < 0.001;工作人员:P < 0.001)。在缝合伤口时,患者、家长和工作人员感知到的两组之间平均和中位数疼痛评分无显著差异。利多卡因组“麻醉失败”(疼痛评分8 - 10)的数量显著更高(P < 0.01)。在直接询问时,AC组84.5%的家长认为总体操作可接受,而利多卡因组为61%的家长(P < 0.01)。两组均无显著并发症。

结论

局部AC应被视为缝合合适儿童裂伤的首选局部麻醉剂。