Christenson J T, Maurice J, Simonet F, Velebit V, Schmuziger M
Unité de chirurgie Cardio-vasculaire, Hôpital de la Tour, Meyrin-Genève.
Swiss Surg Suppl. 1996;Suppl 1:19-22.
The management of patients with coexisting severe carotid and coronary artery disease continues to be controversial. To evaluate the actual risks we have reviewed our experience of 92 patients that underwent simultaneous cardiac surgery and carotid thrombendarterectomy (TEA) over a 10 year period. The mean age was 65 +/- 7 year (41-80), 75% were men. There were 11 REDO cardiac procedures. There were 15 symptomatic and 77 asymptomatic carotid artery stenosis, including 21 with bilateral carotid disease. Mean preop.LVEF was 57.4% (15-80%). Carotid TEA was performed under hypothermia (26 degrees C), preferably with beating heart after an equilibration period of 10 min. The overall mortality was 5.4% (5 patients). 4 of the deaths were reoperative cardiac surgery. Non-fatal myocardial infarction occurred in 1 patient. Postop. neurological complications were diagnosed in 7 patients (8%), 3 transient and 4 permanent neurological deficits occurred. 33 patients had no post-operative complications at all and 25 patients had as only complication, transient arrhythmia. Follow-up revealed a 5-year survival rate of 83% and a cardiac event-free survival of 70%, without neurological events. We therefore conclude that simultaneous carotid TEA and cardiac surgery can be performed using controlled hypothermic cardiopulmonary bypass (26 degrees C), in experienced hands, with an acceptable mortality (5.4%) and low morbidity. Carotid TEA combined with two or more cardiac procedures has the highest mortality and morbidity and should be avoided.
并存严重颈动脉和冠状动脉疾病患者的治疗仍存在争议。为评估实际风险,我们回顾了10年间92例同时接受心脏手术和颈动脉血栓内膜切除术(TEA)患者的经验。平均年龄为65±7岁(41 - 80岁),75%为男性。有11例再次心脏手术。有15例有症状和77例无症状颈动脉狭窄,其中21例为双侧颈动脉疾病。术前平均左室射血分数(LVEF)为57.4%(15 - 80%)。颈动脉TEA在低温(26℃)下进行,最好在平衡10分钟后在心脏跳动下进行。总死亡率为5.4%(5例患者)。4例死亡为再次心脏手术患者。1例发生非致命性心肌梗死。7例患者(8%)术后被诊断有神经并发症,3例为短暂性神经功能缺损,4例为永久性神经功能缺损。33例患者完全没有术后并发症,25例患者仅有的并发症为短暂性心律失常。随访显示5年生存率为83%,无心脏事件生存率为70%,无神经事件发生。因此,我们得出结论,在经验丰富的医生手中,使用控制性低温体外循环(26℃)可同时进行颈动脉TEA和心脏手术,死亡率(5.4%)可接受且发病率低。颈动脉TEA联合两项或更多心脏手术的死亡率和发病率最高,应避免进行。