Kacprzyk F
Klinika Nefrologiczna Instytutu Medycyny Wewnetrznej Akademii Medycznej w Lodzi.
Postepy Hig Med Dosw. 1995;49(4):513-22.
IL-6 synthesized by various types of cells and has multiple biological functions. In the kidney, IL-6 is synthesized by mesangial cells and acts as an autocrine growth factor. IL-6 was demonstrated in the glomerular mesangium and in the urine of patients with proliferative glomerulonephritis, suggesting that it has an important role in the pathogenesis of renal glomerular diseases.
白细胞介素-6由多种类型的细胞合成并具有多种生物学功能。在肾脏中,白细胞介素-6由系膜细胞合成并作为一种自分泌生长因子发挥作用。在增殖性肾小球肾炎患者的肾小球系膜和尿液中证实了白细胞介素-6的存在,这表明它在肾小球疾病的发病机制中起重要作用。