Merriwether D A, Hall W W, Vahlne A, Ferrell R E
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh 15261, USA.
Am J Hum Genet. 1996 Jul;59(1):204-12.
mtDNA RFLP variation was analyzed in 42 Mongolians from Ulan Bator. All four founding lineage types (A [4.76%], B [2.38%], C [11.9%], and D [19.04%]) identified by Torroni and colleagues were detected. Seven of the nine founding lineage types proposed by Bailliet and colleagues and Merriwether and Ferrell were detected (A2 [4.76%], B [2.38%], C1 [11.9%], D1 [7.14%], D2 [11.9%], X6 [16.7%], and X7 [9.5%]). Sixty-four percent of these 42 individuals had "Amerindian founding lineage" haplotypes. A survey of 24 restriction sites yielded 16 polymorphic sites and 21 different haplotypes. The presence of all four of the founding lineages identified by the Torroni group (and seven of Merriwether and Ferrell's nine founding lineages), combined with Mongolia's location with respect to the Bering Strait, indicates that Mongolia is a potential location for the origin of the founders of the New World. Since lineage B, which is widely distributed in the New World, is absent in Siberia, we conclude that Mongolia or a geographic location common to both contemporary Mongolians and American aboriginals is the more likely origin of the founders of the New World.
对来自乌兰巴托的42名蒙古人进行了线粒体DNA限制性片段长度多态性（mtDNA RFLP）变异分析。检测到了Torroni及其同事鉴定出的所有四种奠基谱系类型（A [4.76%]、B [2.38%]、C [11.9%]和D [19.04%]）。检测到了Bailliet及其同事以及Merriwether和Ferrell提出的九种奠基谱系类型中的七种（A2 [4.76%]、B [2.38%]、C1 [11.9%]、D1 [7.14%]、D2 [11.9%]、X6 [16.7%]和X7 [9.5%]）。这42名个体中有64%具有“美洲印第安人奠基谱系”单倍型。对24个限制位点的调查产生了16个多态性位点和21种不同的单倍型。Torroni团队鉴定出的所有四种奠基谱系（以及Merriwether和Ferrell的九种奠基谱系中的七种）的存在，再加上蒙古相对于白令海峡的地理位置，表明蒙古是新世界奠基者起源的一个潜在地点。由于在西伯利亚不存在广泛分布于新世界的谱系B，我们得出结论，蒙古或当代蒙古人和美洲原住民共有的地理位置更有可能是新世界奠基者的起源地。
