Assignment of the porcine obese (leptin) gene to chromosome 18 by linkage analysis of a new PCR-based polymorphism.

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作者信息

Sasaki S, Clutter A C, Pomp D

机构信息

Department of Animal Science, Oklahoma State University, Stilwater, Oklahoma 74078-0425, USA.

出版信息

Mamm Genome. 1996 Jun;7(6):471-2. doi: 10.1007/s003359900141.

DOI:10.1007/s003359900141

PMID:8662239

Abstract

摘要

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本文引用的文献

Positional cloning of the mouse obese gene and its human homologue.小鼠肥胖基因及其人类同源基因的定位克隆。

Nature. 1994 Dec 1;372(6505):425-32. doi: 10.1038/372425a0.

Enhanced expression of rat obese (ob) gene in adipose tissues of ventromedial hypothalamus (VMH)-lesioned rats.

Biochem Biophys Res Commun. 1995 Jun 15;211(2):469-75. doi: 10.1006/bbrc.1995.1837.

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.反对人类肥胖中存在过早终止密码子或缺乏肥胖基因信使核糖核酸的证据。

J Clin Invest. 1995 Jun;95(6):2986-8. doi: 10.1172/JCI118007.

Weight-reducing effects of the plasma protein encoded by the obese gene.肥胖基因编码的血浆蛋白的减肥作用。

Science. 1995 Jul 28;269(5223):543-6. doi: 10.1126/science.7624777.

Effects of the obese gene product on body weight regulation in ob/ob mice.肥胖基因产物对ob/ob小鼠体重调节的影响。

Science. 1995 Jul 28;269(5223):540-3. doi: 10.1126/science.7624776.

Localization of the human OB gene (OBS) to chromosome 7q32 by fluorescence in situ hybridization.

Genomics. 1995 Aug 10;28(3):603-4. doi: 10.1006/geno.1995.1201.

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.实验动物中的下丘脑性肥胖和遗传性肥胖：一种自主神经和内分泌假说。

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