Cuparencu B, Sandor V
Pharmacology. 1977;15(3):218-26. doi: 10.1159/000136692.
In reserpine-induced ulcers in rats, the centrally acting sympathomimetic ámines (amphetamine, mephentermine and ephedrine) produced a significant protection. Only amphetamine had a beneficial effect in restraint ulcers. Tyramine, a preponderant peripherally acting sympathominetic amine, was inefficient in both experimental models. It is suggested that the protective activity is due to the influence of these amines on the adrenergic structures, mainly at central level.
在利血平诱发的大鼠溃疡中，中枢作用的拟交感胺（苯丙胺、美芬丁胺和麻黄碱）产生了显著的保护作用。只有苯丙胺对束缚性溃疡有有益作用。酪胺是一种主要在外周起作用的拟交感胺，在这两种实验模型中均无效。提示这种保护活性是由于这些胺对肾上腺素能结构的影响，主要是在中枢水平。
