van Hoeven K H, Bertolini P K
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107, USA.
Acta Cytol. 1996 May-Jun;40(3):489-95. doi: 10.1159/000333904.
To determine the prevalence of fiber contaminants, to provide morphologic descriptions of various fiber types and to try to understand the significance of their presence in cervical smears.
Fibers from cotton swab tips, hair, cardboard slide transporters, Cytobrush bristles and three commercial brands of tampons were smeared onto glass slides, Papanicolaou stained and examined. Then a prospective study of consecutively screened cervicovaginal smears from 1,368 women was undertaken to identify fiber contaminants.
Fibers were identified in 178 cases (13%). In 120, the fibers were considered extrinsic, commonly having the microscopic features of cardboard. In 58, the fibers were considered to be intrinsic to the smear because of their presence in the same plane and alignment as the cells, an associated inflammatory cell reaction, and adherent or absorbed cellular products, occasionally hemosiderin. The most common intrinsic fibers were cotton and rayon. No statistically significant relationship was identified for the presence of intrinsic fibers and patients' ages, stated menstrual dates or pathologic lesions.
Fiber contaminants are commonly present in cervicovaginal smears, usually do not originate in the patient (are "extrinsic") and have no pathologic significance. Knowledge of the microscopic features of fiber contaminants enables them to be identified confidently and distinguished from fungal hyphae and other filamentous pathogens.
确定纤维污染物的患病率，提供各种纤维类型的形态学描述，并试图了解它们在宫颈涂片检查中出现的意义。
将棉签头、毛发、纸板载玻片运输器、细胞刷刷毛以及三个商业品牌卫生棉条中的纤维涂抹在载玻片上，进行巴氏染色并检查。然后对1368名女性连续筛查的宫颈阴道涂片进行前瞻性研究，以识别纤维污染物。
在178例（13%）中发现了纤维。其中120例中的纤维被认为是外源性的，通常具有纸板的微观特征。在58例中，由于纤维与细胞处于同一平面且排列一致、伴有炎性细胞反应以及附着或吸附细胞产物（偶尔为含铁血黄素），纤维被认为是涂片固有的。最常见的固有纤维是棉花和人造丝。未发现固有纤维的存在与患者年龄、所述月经日期或病理病变之间存在统计学上的显著关系。
纤维污染物在宫颈阴道涂片中普遍存在，通常并非源于患者（即“外源性”），且无病理意义。了解纤维污染物的微观特征有助于准确识别它们，并将其与真菌菌丝和其他丝状病原体区分开来。
