Bøggild H, Tüchsen F, Orhede E
Department of Occupational Medicine, Aalborg Regional Hospital, P O Box 561, DK-9100 Aalborg, Denmark.
Int J Epidemiol. 1996 Jun;25(3):630-7. doi: 10.1093/ije/25.3.630.
Certain occupational groups have formerly been identified as having higher risks of suffering from chronic inflammatory bowel diseases. These were evaluated in an independent data set.
A cohort, comprising all 2 273 872 male and female Danes aged 20-59 years on 1 January 1986 were followed up for hospitalizations due to chronic inflammatory bowel disease until 31 December 1990.
From 1981 to 1990 6296 first time admissions occurred. The incidence increased from 1981-1985 to 1986-1990. Of 363 male and 213 female occupational groups eight and five groups respectively had statistically significant raised standardized hospitalization ratios. Among 15 groups previously found to have significant odds ratios only female office staff and health occupations were found to have statistically significant raised standardized hospitalization ratios. Ratios for occupational groups with non-daytime work were not statistically significant. Compared to occupations without sedentary work occupations with predominantly sedentary work had a standardized hospitalization ratio of 125 (95% confidence interval [95% CI] : 116.9-133.1). Self-employed had low hospitalization rates, while 'other salaried staff' and 'not economically active' had high rates.
We found no consistent pattern of occupations at increased risk except that sedentary work may increase the risk of attracting chronic inflammatory bowel disease.
某些职业群体先前被认定患慢性炎症性肠病的风险较高。在一个独立数据集中对这些群体进行了评估。
一个队列包括1986年1月1日所有年龄在20 - 59岁的2273872名丹麦男女,随访至1990年12月31日因慢性炎症性肠病住院的情况。
1981年至1990年发生了6296例首次入院。发病率从1981 - 1985年到1986 - 1990年有所上升。在363个男性职业群体和213个女性职业群体中,分别有8个和5个群体的标准化住院率有统计学意义的升高。在先前发现有显著优势比的15个群体中,只有女性办公室职员和卫生职业群体的标准化住院率有统计学意义的升高。从事非白天工作职业群体的比率无统计学意义。与非久坐工作的职业相比,主要为久坐工作的职业标准化住院率为125(95%置信区间[95%CI]:116.9 - 133.1)。个体经营者住院率低,而“其他受薪员工”和“无经济活动者”住院率高。
我们发现除久坐工作可能增加患慢性炎症性肠病的风险外,没有一致的职业风险增加模式。