Meringova L F, Kramskaia T A, Dukhin A I, Iakovleva I V, Chetverikova L K, Poliak R Ia
Vestn Ross Akad Med Nauk. 1996(3):34-7.
The effect of the antioxidant ionol on a humoral immune response was studied in experimental influenza. With preventive introduction of ionol, the affinity of anti-influenza G antibodies circulating in the blood stream was shown to be decreased as compared to that in control animals. The changes in the affinity during influenza infection were cyclic and less marked in the group of animals receiving ionol. The administration of the antioxidant substantially reduced the detection rate of specific blood immune complexes and contributed to the production of antibody-forming cells. The findings suggest that ionol has a favourable effect on a humoral immune response in experimental influenza and alleviates the course of an infectious process.
在实验性流感中研究了抗氧化剂紫罗兰醇对体液免疫反应的影响。预防性引入紫罗兰醇后，与对照动物相比，血流中循环的抗流感G抗体的亲和力降低。流感感染期间亲和力的变化呈周期性，在接受紫罗兰醇的动物组中不太明显。给予抗氧化剂可显著降低特异性血液免疫复合物的检出率，并有助于抗体形成细胞的产生。这些发现表明，紫罗兰醇对实验性流感中的体液免疫反应有有利影响，并减轻了感染过程的进程。
