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Immunoglobulin diversity: rearranging by cutting and repairing.

作者信息

Lieber M

机构信息

Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

出版信息

Curr Biol. 1996 Feb 1;6(2):134-6. doi: 10.1016/s0960-9822(02)00443-8.

DOI:10.1016/s0960-9822(02)00443-8
PMID:8673457
Abstract

The recombination process that assembles antigen-receptor genes is now understood in some biochemical detail. The initial steps reflect a common theme seen in retroviral integration and prokaryotic transposition, and the later steps involve the enzymatic machinery for double-strand break DNA repair.

摘要

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