IncN 质粒 R46 的抗砷操纵子。
The arsenical resistance operon of IncN plasmid R46.
作者信息
Bruhn D F, Li J, Silver S, Roberto F, Rosen B P
机构信息
Biotechnologies Department, Idaho National Engineering Laboratory, Idaho Falls 83415-2203, USA.
出版信息
FEMS Microbiol Lett. 1996 Jun 1;139(2-3):149-53. doi: 10.1111/j.1574-6968.1996.tb08195.x.
The arsenical resistance operon of the IncN plasmid R46 consists of 4696 bp and starts with predicted transcriptional control and initiation signals, followed by five genes, arsD, arsA, and arsC. The corresponding Escherichia coli chromosomal ars operon and two staphylococcal ars operons lack arsA and arsD genes. The R46 system contains only the second known versions of arsA and arsD, after those of plasmid R773. Western blot analysis identified the R46 proteins using antibodies against R773 ArsA, ArsD and ArsR.
IncN 质粒 R46 的抗砷操纵子由 4696 个碱基对组成，起始于预测的转录控制和起始信号，随后是五个基因，即 arsD、arsA 和 arsC。相应的大肠杆菌染色体抗砷操纵子以及两个葡萄球菌抗砷操纵子缺少 arsA 和 arsD 基因。R46 系统包含继质粒 R773 之后第二个已知版本的 arsA 和 arsD。蛋白质印迹分析使用针对 R773 ArsA、ArsD 和 ArsR 的抗体鉴定了 R46 蛋白。
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