Volkov G L
Ukr Biokhim Zh. 1977 Mar-Apr;49(2):88-90.
The content of collagen in the bone tissue of rats and incorporation of 14C from 2-14C-glycin into it were studied as affected by vitamin D deficiency. It is established that under experimental rachitis intensity of the radioactive label incorporation into soluble collagen is 1.7 times as low as in the norm. A decrease in the amount of the collagen soluble fraction and accumulation of its insoluble fraction and distribution of radioactivity in these fractions might evidence for rapid "ripening" of soluble collagen in the rats with D-hypovitaminosis.
研究了维生素D缺乏对大鼠骨组织中胶原蛋白含量以及2-¹⁴C-甘氨酸中¹⁴C掺入情况的影响。结果表明，在实验性佝偻病状态下，放射性标记掺入可溶性胶原蛋白的强度比正常情况低1.7倍。可溶性胶原蛋白部分的量减少，其不溶性部分积累，以及放射性在这些部分中的分布，可能证明维生素D缺乏的大鼠体内可溶性胶原蛋白快速“成熟”。
