Nugent C E, Punch M R, Barr M, LeBlanc L, Johnson M P, Evans M I
Department of Obstetrics and Gynecology, University of Michigan, Detroit, USA.
Obstet Gynecol. 1996 May;87(5 Pt 2):829-31.
Triploid molar pregnancies are usually managed by evacuation of the uterine contents.
A 25-year-old woman had a clomiphene citrate-induced twin pregnancy. Ultrasound scan at 13 weeks revealed one anomalous twin. Cytogenetic analysis revealed a karyotype of 69, XXY and a normal other twin. In an attempt to salvage the normal fetus, selective termination was successfully performed at 15 weeks by intracardiac potassium chloride injection. However, the placenta continued to grow and severe preeclampsia developed at 19 weeks, requiring pregnancy termination.
Selective termination of a triploid twin does not guarantee resolution of molar growth and sequelae of the mole; severe preeclampsia can still develop.
三倍体葡萄胎妊娠通常通过清宫来处理。
一名25岁女性因克罗米芬诱导而怀有双胎妊娠。孕13周时超声检查发现一个胎儿异常。细胞遗传学分析显示其中一个胎儿核型为69, XXY，另一个胎儿正常。为挽救正常胎儿，在孕15周时通过心内注射氯化钾成功实施了选择性终止妊娠。然而，胎盘持续生长，孕19周时发生了严重子痫前期，需要终止妊娠。
选择性终止三倍体双胎中的异常胎儿并不能保证葡萄胎生长及葡萄胎后遗症的消退；仍可能发生严重子痫前期。
