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缓慢注射前列腺素E1可减轻相关的阴茎疼痛。

Slow injection of prostaglandin E1 decreases associated penile pain.

作者信息

Gheorghiu D, Godschalk M, Gheorghiu S, Mulligan T

机构信息

Division of Geriatrics Medicine, Medical College of Virginia, Richmond, USA.

出版信息

Urology. 1996 Jun;47(6):903-4. doi: 10.1016/S0090-4295(96)00065-9.

Abstract

OBJECTIVES

A randomized, double-blind study to determine whether speed of intracavernous injection of prostaglandin E1 (PGE1) is associated with pain.

METHODS

On two separate occasions, using two different speeds of injection (5 versus 60 seconds), 11 subjects received the same dose of PGE1 that they used at home. The presence, duration, and intensity of pain were recorded.

RESULTS

We found that fast penile injection of PGE1 was associated with a greater intensity of pain (P = 0.04).

CONCLUSIONS

Slow injection of PGE1 is less often associated with penile pain, the most common adverse effect of this treatment.

摘要

目的

一项随机双盲研究,以确定海绵体内注射前列腺素E1(PGE1)的速度是否与疼痛相关。

方法

在两个不同的场合,11名受试者以两种不同的注射速度(5秒与60秒)接受了与他们在家中使用的相同剂量的PGE1。记录疼痛的存在、持续时间和强度。

结果

我们发现快速阴茎注射PGE1与更强的疼痛强度相关(P = 0.04)。

结论

缓慢注射PGE1较少与阴茎疼痛相关,阴茎疼痛是这种治疗最常见的不良反应。

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