Godschalk M, Gheorghiu D, Katz P G, Mulligan T
Division of Geriatric Medicine, Medical College of Virginia, Richmond, USA.
J Urol. 1996 Sep;156(3):999-1000.
A prospective, randomized, double-blind study was done to determine whether alkalization of prostaglandin E1 decreases pain associated with intracavernous injection.
Ten subjects with a history of pain following at least 70% of injections of prostaglandin E1 received 2 injections of prostaglandin E1, 1 with and 1 without sodium bicarbonate. Patients reported the duration and intensity of pain following each injection.
Comparing injections of prostaglandin E1 with and without bicarbonate, there were no significant differences in number of subjects reporting pain, or duration and intensity of pain.
Addition of sodium bicarbonate does not alleviate penile pain associated with injection of prostaglandin E1.
进行一项前瞻性、随机、双盲研究，以确定前列腺素E1碱化是否能减轻海绵体内注射相关的疼痛。
10名在至少70%的前列腺素E1注射后有疼痛史的受试者接受了2次前列腺素E1注射，1次添加碳酸氢钠，1次不添加。患者报告每次注射后疼痛的持续时间和强度。
比较添加和不添加碳酸氢钠的前列腺素E1注射，在报告疼痛的受试者数量、疼痛持续时间和强度方面没有显著差异。
添加碳酸氢钠不能减轻与注射前列腺素E1相关的阴茎疼痛。
