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与使用一种中草药产品麻黄相关的急性肝炎。

Acute hepatitis associated with the use of a Chinese herbal product, ma-huang.

作者信息

Nadir A, Agrawal S, King P D, Marshall J B

机构信息

Division of Gastroenterology, University of Missouri Hospital and Clinics, Columbia 65212, USA.

出版信息

Am J Gastroenterol. 1996 Jul;91(7):1436-8.

PMID:8678010
Abstract

Herbal medicines are widely perceived by the public as being healthful and innocuous. A number of herbal medicines have now been linked with hepatotoxicity. We report a case of acute hepatitis associated with the use of ma-huang, a herbal product derived from plants of the Ephedra species, which is advertised as being useful for causing weight loss and enhancing energy levels. Given the lack of reports in the literature of hepatotoxicity with ma-huang and ephedrine, we speculate that the ma-huang product our patient took contained some other ingredient or contaminant or was misidentified. Our report and others in the literature, which we review, indicate that the clinician should consider herbal medicines as a possible cause of unexplained liver injury.

摘要

草药被公众广泛认为是有益健康且无害的。现在已有多种草药与肝毒性有关。我们报告一例急性肝炎病例,该病例与服用麻黄有关,麻黄是一种源自麻黄属植物的草药产品,宣传称其有助于减肥和提高精力水平。鉴于文献中缺乏麻黄和麻黄碱肝毒性的报道,我们推测我们的患者服用的麻黄产品含有其他成分或污染物,或者被误认了。我们的报告以及我们所回顾的文献中的其他报告表明,临床医生应将草药视为不明原因肝损伤的可能原因。

相似文献

1
Acute hepatitis associated with the use of a Chinese herbal product, ma-huang.与使用一种中草药产品麻黄相关的急性肝炎。
Am J Gastroenterol. 1996 Jul;91(7):1436-8.
2
The irony of herbal hepatitis: Ma-Huang-induced hepatotoxicity associated with compound heterozygosity for hereditary hemochromatosis.草药性肝炎的讽刺之处:麻黄引起的肝毒性与遗传性血色素沉着症的复合杂合性相关。
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Ma-huang strikes again: ephedrine nephrolithiasis.麻黄再次作祟:麻黄碱肾结石症
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Cytotoxicity assessment of Ma-huang (Ephedra) under different conditions of preparation.不同制备条件下麻黄的细胞毒性评估。
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Herbal formulation MIT ameliorates high-fat diet-induced non-alcoholic fatty liver disease.
草药配方MIT可改善高脂饮食诱导的非酒精性脂肪性肝病。
Integr Med Res. 2020 Dec;9(4):100422. doi: 10.1016/j.imr.2020.100422. Epub 2020 May 14.
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Clin Liver Dis (Hoboken). 2016 Nov 10;8(Suppl 1):S30-S33. doi: 10.1002/cld.597. eCollection 2016 Nov.
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Liver injury due to herbal and dietary supplements: A review of individual ingredients.草药和膳食补充剂导致的肝损伤:单一成分综述
Clin Liver Dis (Hoboken). 2016 Apr 27;7(4):80-83. doi: 10.1002/cld.541. eCollection 2016 Apr.
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Sympathomimetic amine compounds and hepatotoxicity: Not all are alike-Key distinctions noted in a short review.拟交感神经胺类化合物与肝毒性:并非所有都相同——一篇简短综述中指出的关键区别
Toxicol Rep. 2018 Dec 1;6:26-33. doi: 10.1016/j.toxrep.2018.11.013. eCollection 2019.
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Traditional Chinese Medicine (TCM) and Herbal Hepatotoxicity: RUCAM and the Role of Novel Diagnostic Biomarkers Such as MicroRNAs.传统中医与草药肝毒性:RUCAM及微小RNA等新型诊断生物标志物的作用
Medicines (Basel). 2016 Jul 19;3(3):18. doi: 10.3390/medicines3030018.
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