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全甲状腺切除术在分化型甲状腺癌治疗中的应用

Completion total thyroidectomy in the management of differentiated thyroid carcinoma.

作者信息

Agarwal A, Mishra S K

机构信息

Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

出版信息

Aust N Z J Surg. 1996 Jun;66(6):358-60. doi: 10.1111/j.1445-2197.1996.tb01210.x.

DOI:10.1111/j.1445-2197.1996.tb01210.x
PMID:8678852
Abstract

BACKGROUND

Completion thyroidectomy is the removal of any thyroid tissue that remains after a less than total thyroidectomy. This procedure has been commonly performed when the final histopathology of the excised ipsilateral thyroid lobe reveals papillary or follicular carcinoma of the thyroid. Complete thyroidectomy carries little morbidity if performed by experienced surgeons using a lateral approach. The purpose of this study is to reinforce the usefulness of a lateral approach.

METHODS

A retrospective analysis over a 5 year period at the Department of Endocrine Surgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS) yielded 19 patients who underwent completion thyroidectomy. This group represents 23% of 82 patients who underwent total thyroidectomy for differentiated thyroid cancer (DTC) during that period. The residual thyroid tissue was excised through a lateral approach and could be resected safely, preserving the recurrent laryngeal nerve (RLN) and the parathyroid glands.

RESULTS

A lateral approach dissection could be performed with ease in a virgin area. Excision of residual thyroid tissue could be performed safely even in cases with prior partial lobectomy or bilateral subtotal resection. Tumour was found in 52% of the re-operative specimens: in three out of four of those after a previous partial lobectomy, in six out of 12 of those after a total lobectomy, and in one out of three of those after a prior bilateral (although incomplete) thyroid resection. Postoperative complications included transient RLN palsy (n = 2) and transient hypoparathyroidism (n = 4).

CONCLUSIONS

Completion thyroidectomy using a lateral approach is safe in re-operative thyroid surgery.

摘要

背景

甲状腺次全切除术后,完成甲状腺切除术是指切除剩余的任何甲状腺组织。当切除的同侧甲状腺叶最终组织病理学检查显示为甲状腺乳头状癌或滤泡状癌时,通常会进行此手术。如果由经验丰富的外科医生采用外侧入路进行完全甲状腺切除术,则并发症很少。本研究的目的是强化外侧入路的实用性。

方法

对桑贾伊·甘地医学科学研究生学院(SGPGIMS)内分泌外科5年期间的病例进行回顾性分析,有19例患者接受了完成甲状腺切除术。该组占同期82例因分化型甲状腺癌(DTC)接受全甲状腺切除术患者的23%。通过外侧入路切除残留的甲状腺组织,并且可以安全地切除,同时保留喉返神经(RLN)和甲状旁腺。

结果

在未手术过的区域可以轻松进行外侧入路解剖。即使在先前进行过部分叶切除术或双侧次全切除术的病例中,也可以安全地切除残留的甲状腺组织。在52%的再次手术标本中发现肿瘤:在先前进行过部分叶切除术的患者中,四分之三发现肿瘤;在全叶切除术后的12例患者中,6例发现肿瘤;在先前进行过双侧(尽管不完全)甲状腺切除术后的3例患者中,1例发现肿瘤。术后并发症包括短暂性RLN麻痹(n = 2)和短暂性甲状旁腺功能减退(n = 4)。

结论

在再次甲状腺手术中,采用外侧入路进行完成甲状腺切除术是安全的。

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Completion total thyroidectomy in the management of differentiated thyroid carcinoma.全甲状腺切除术在分化型甲状腺癌治疗中的应用
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