Goodwin A
Prof Care Mother Child. 1995;5(1):7-9.
Nebulised steroids are a very effective form of treatment. A very small dose of steroids is inhaled from a nebuliser in the form of a fine spray of minute droplets which allows the drug to be spread over a wide area of the lungs and rapidly absorbed. Nebulisers can be used from one month old upwards, e.g. in wheezy infants and toddlers. Very ill children too breathless to use other types of inhaler often benefit from a nebulised therapy. Nebulisers often improve compliance, particularly with toddlers. In many children, nebulised therapy maintains lung function as effectively as oral prednisolone, while minimising the risk of systemic side-effects and improving the patient's quality of life. Experienced primary health-care teams can start a child on nebulised therapy in the community, but it should ideally be initiated in conjunction with a local paediatrician skilled in asthma management. Well managed nebuliser therapy can help prevent hospital admissions.
雾化吸入类固醇是一种非常有效的治疗方式。极少量的类固醇以微小液滴的细雾形式从雾化器中吸入,这使得药物能够在肺部广泛区域扩散并迅速吸收。雾化器从1个月大的婴儿起就可以使用,例如用于喘息的婴幼儿。病情非常严重、呼吸急促以至于无法使用其他类型吸入器的儿童,常常受益于雾化治疗。雾化器通常能提高依从性,尤其是对于幼儿。在许多儿童中,雾化治疗维持肺功能的效果与口服泼尼松龙一样有效,同时将全身副作用的风险降至最低,并改善患者的生活质量。经验丰富的初级卫生保健团队可以在社区中让儿童开始接受雾化治疗,但理想情况下,应与擅长哮喘管理的当地儿科医生联合开展。管理良好的雾化治疗有助于预防住院。