Takach T J, Ott D A, Reul G J, Duncan J M, Livesay J J, Cooley D A
Division of Cardiovascular Surgery, Texas Heart Institute, Houston 77030, USA.
Tex Heart Inst J. 1996;23(1):42-4.
Objective evidence of the benefit of carotid endarterectomy in preventing stroke and its significant sequelae has recently been demonstrated by prospective trials. The salutary results depend on meeting strict operative outcome criteria as established by the American Heart Association. We retrospectively analyzed 265 consecutive carotid endarterectomies performed in 248 patients during 1 year at our institution. The perioperative mortality rate was 0; late mortality occurred 6 months postoperatively in 1 of 2 patients who experienced a perioperative stroke. The combined perioperative mortality and stroke rate was 0.8%. The combined mortality and stroke rate in patient subgroups was 0.7% (1/151) for asymptomatic patients, 1.6% (1/64) for symptomatic patients who had presented with a transient ischemic attack, and 0% (0/50) for symptomatic patients who had presented with a completed stroke. We conclude that the objective postoperative benefits of carotid endarterectomy in treating extracranial cerebrovascular disease can be achieved with low perioperative patient morbidity.
近期的前瞻性试验已证实了颈动脉内膜切除术在预防中风及其严重后遗症方面的益处的客观证据。有益的结果取决于满足美国心脏协会制定的严格手术结果标准。我们回顾性分析了本机构在1年内对248例患者连续进行的265例颈动脉内膜切除术。围手术期死亡率为0;2例围手术期中风患者中有1例在术后6个月发生晚期死亡。围手术期死亡率和中风率合并为0.8%。无症状患者亚组的死亡率和中风率合并为0.7%(1/151),出现短暂性脑缺血发作的症状性患者为1.6%(1/64),出现完全性中风的症状性患者为0%(0/50)。我们得出结论,颈动脉内膜切除术治疗颅外脑血管疾病的术后客观益处可在围手术期患者低发病率的情况下实现。