Mathur S, Achari A, Green L, Anand B S
Department of Internal Medicine, V.A. Medical Center, Houston, TX 77030, USA.
J Gastroenterol. 1996 Apr;31(2):273-7. doi: 10.1007/BF02389530.
Varicella (chicken pox) is a common viral infection in children and generally runs a benign course. However, in adults, and especially in immunocompromised subjects such as those on immunosuppressant therapy or with AIDS, varicella infection is particularly severe and is associated with the formation of hemorrhagic skin lesions and visceral involvement. These patients are at an increased risk of developing varicella hepatitis, which frequently results in fulminant hepatic failure and death. In the present report, we describe for the first time the course of disease and the histological appearance of varicella hepatitis in a patient infected with the human T cell lymphotropic viruses (HTLV) I and II; these viruses have many characteristics in common with the human immunodeficiency virus (HIV). Our patient had a relatively benign illness, suggesting that varicella infection in the presence of HTLVI and II may not run as severe a course as it does in patients with HIV infection.
水痘是儿童常见的病毒感染，通常病程良性。然而，在成人中，尤其是在免疫功能低下的人群中，如接受免疫抑制治疗的患者或艾滋病患者，水痘感染特别严重，并伴有出血性皮肤病变和内脏受累。这些患者发生水痘性肝炎的风险增加，水痘性肝炎常导致暴发性肝衰竭和死亡。在本报告中，我们首次描述了一名感染人类嗜T细胞病毒（HTLV）I型和II型的患者水痘性肝炎的病程及组织学表现；这些病毒与人类免疫缺陷病毒（HIV）有许多共同特征。我们的患者病情相对较轻，这表明在HTLV I型和II型感染的情况下，水痘感染的病程可能不像HIV感染患者那样严重。
