[The structural-metabolic bases of the action of vibration on the thalamic structures of the brain].

By means of histochemistry and light and electron microscopy one of the links of the postero-ventro-lateral thalamus (PVLT) exposed to the vibration of low frequency (VLF) (95 dB, 8 Hz) was studied. Diffuse mild alterations of PVLT of dystrophic or compensatory nature resembling that in hypoxia were discovered. Disturbances of oxidative metabolism (activation of succinic acid oxidase link of Krebs cycle, use of NADPH potentials and pentose cycle energy in neurons energetics) were alike with that in hypoxia. Shortening of active zone, astrocyte muff presence, overloading with vesicles were found in synapses. Interneuronal contacts disturbance combined with hypoxic alterations appears to be an important mechanism, resulting in negative consequences of the vibration effect.