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由生物I型流感嗜血杆菌隐匿基因种引起的菌血症和绒毛膜羊膜炎。

Bacteremia and chorioamnionitis due to cryptic genospecies of Haemophilus Influenzae biotype I.

作者信息

Gill M V, Schoch P E, Musser J M, Cunha B A

机构信息

Infectious Disease Division, Winthrop-University Hospital, Mineola, NY 11501, USA.

出版信息

Eur J Clin Microbiol Infect Dis. 1995 Dec;14(12):1088-90. doi: 10.1007/BF01590945.

DOI:10.1007/BF01590945
PMID:8681986
Abstract

Nontypable strains of Haemophilus influenzae are well-known causes of maternal and neonatal infections. Using DNA-DNA hybridization techniques, some of these strains have been shown to belong to a cryptic genospecies of Haemophilus, which is distantly related to Haemophilus influenzae and Haemophilus hemolyticus. This report describes the first case of sepsis and chorioamnionitis due to Haemophilus influenzae biotype I, which was identified using the RapIDNH system and then confirmed by multilocus enzyme electrophoresis to belong to this cryptic genospecies of Haemophilus. The electromorph type 92 of the isolate was consistent with that of biotype I of the cryptic genospecies.

摘要

不可分型流感嗜血杆菌是引起孕产妇和新生儿感染的常见病因。运用DNA-DNA杂交技术,已证实其中一些菌株属于流感嗜血杆菌的一个隐匿基因种,该基因种与流感嗜血杆菌和溶血嗜血杆菌亲缘关系较远。本报告描述了首例由I型流感嗜血杆菌引起的败血症和绒毛膜羊膜炎病例,该菌株先用RapID NH系统鉴定,随后通过多位点酶电泳确认属于流感嗜血杆菌的这一隐匿基因种。分离菌株的电泳型92与该隐匿基因种的I型一致。

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本文引用的文献

1
Adherence to human cells of a cryptic Haemophilus genospecies responsible for genital and neonatal infections.一种导致生殖器和新生儿感染的隐秘嗜血杆菌基因组种对人类细胞的黏附。
Infect Immun. 1993 Oct;61(10):4112-8. doi: 10.1128/iai.61.10.4112-4118.1993.
2
Genetic characterization of a cryptic genospecies of Haemophilus causing urogenital and neonatal infections.一种引起泌尿生殖系统和新生儿感染的隐秘嗜血杆菌基因种的基因特征分析。
J Clin Microbiol. 1993 May;31(5):1111-6. doi: 10.1128/jcm.31.5.1111-1116.1993.
3
Nontypable Haemophilus influenzae (biotype 4) as a neonatal, maternal, and genital pathogen.
使用针对编码16S rRNA的基因的特异性引物,通过聚合酶链反应(PCR)对引起泌尿生殖系统和新生儿感染的嗜血杆菌隐性基因种进行基因鉴定。
J Clin Microbiol. 1996 Jun;34(6):1380-5. doi: 10.1128/jcm.34.6.1380-1385.1996.
不可分型流感嗜血杆菌(生物4型)作为新生儿、产妇及生殖系统病原体
Rev Infect Dis. 1983 Jan-Feb;5(1):123-36. doi: 10.1093/clinids/5.1.123.
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Genetic relationships of serologically nontypable and serotype b strains of Haemophilus influenzae.流感嗜血杆菌血清学不可分型及b型菌株的遗传关系。
Infect Immun. 1986 Apr;52(1):183-91. doi: 10.1128/iai.52.1.183-191.1986.
5
Typing of urogenital, maternal, and neonatal isolates of Haemophilus influenzae and Haemophilus parainfluenzae in correlation with clinical source of isolation and evidence for a genital specificity of H. influenzae biotype IV.流感嗜血杆菌和副流感嗜血杆菌泌尿生殖系统、母体及新生儿分离株的分型与分离临床来源的相关性以及流感嗜血杆菌生物IV型的生殖器官特异性证据
J Clin Microbiol. 1989 Oct;27(10):2286-94. doi: 10.1128/jcm.27.10.2286-2294.1989.
6
Methods of multilocus enzyme electrophoresis for bacterial population genetics and systematics.用于细菌群体遗传学和系统学的多位点酶电泳方法。
Appl Environ Microbiol. 1986 May;51(5):873-84. doi: 10.1128/aem.51.5.873-884.1986.
7
Urogenital, maternal and neonatal isolates of Haemophilus influenzae: identification of unusually virulent serologically non-typable clone families and evidence for a new Haemophilus species.流感嗜血杆菌的泌尿生殖系统、母体及新生儿分离株:异常毒力血清不可分型克隆家族的鉴定及一种新流感嗜血杆菌物种的证据
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